Related Experiment Video
Updated: Jul 5, 2026

Robotically Delivered fMRI-Guided Personalized Transcranial Magnetic Stimulation Therapy for Treatment-Resistant Depression
Published on: April 10, 2026
Computer-assisted delivery of cognitive-behavioral therapy for addiction: a randomized trial of CBT4CBT
Kathleen M Carroll1, Samuel A Ball, Steve Martino
1Division of Substance Abuse, Yale University School of Medicine, 950 Campbell Ave., 151D, West Haven, CT 06516, USA. kathleen.carroll@yale.edu
Objectives:
This study evaluated the efficacy of a computer-based version of cognitive-behavioral therapy (CBT) for substance dependence.
Method:
This was a randomized clinical trial in which 77 individuals seeking treatment for substance dependence at an outpatient community setting were randomly assigned to standard treatment or standard treatment with biweekly access to computer-based training in CBT (CBT4CBT) skills.
Results:
Treatment retention and data availability were comparable across the treatment conditions. Participants assigned to the CBT4CBT condition submitted significantly more urine specimens that were negative for any type of drugs and tended to have longer continuous periods of abstinence during treatment. The CBT4CBT program was positively evaluated by participants. In the CBT4CBT condition, outcome was more strongly associated with treatment engagement than in treatment as usual; furthermore, completion of homework assignments in CBT4CBT was significantly correlated with outcome and a significant predictor of treatment involvement.
Conclusions:
These data suggest that CBT4CBT is an effective adjunct to standard outpatient treatment for substance dependence and may provide an important means of making CBT, an empirically validated treatment, more broadly available.
Related Concept Videos
Rational Emotive Behavior Therapy
Cognitive Therapy
Operant Conditioning Intervention
In operant conditioning, behaviors that are...
Modeling in Therapy
Participant Modeling
Participant modeling involves therapists demonstrating calm and effective behaviors in situations...
Behavior Therapy
Exposure therapy is a cornerstone of behavioral treatment for anxiety disorders. It involves systematic exposure to feared stimuli, either in real...
Electroconvulsive Therapy
