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Updated: Jul 5, 2026

Systematic Approach to Identify Novel Antimicrobial and Antibiofilm Molecules from Plants' Extracts and Fractions to Prevent Dental Caries

Systematic Approach to Identify Novel Antimicrobial and Antibiofilm Molecules from Plants' Extracts and Fractions to Prevent Dental Caries

Published on: March 31, 2021

Caries and restoration prevention.

Ivar A Mjör¹, Dorthe Holst, Harald M Eriksen

¹University of Florida College of Dentistry, Gainesville, FL 32610, USA. imjor@dental.ufl.edu

Journal of the American Dental Association (1939)

|May 3, 2008

Summary

This summary is machine-generated.

Active fluoride therapy and updated restoration criteria significantly reduced decayed, missing, and filled (DMF) rates in Norway. This approach lowered the need for dental restorations in both adults and adolescents over 30 years.

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Last Updated: Jul 5, 2026

Systematic Approach to Identify Novel Antimicrobial and Antibiofilm Molecules from Plants' Extracts and Fractions to Prevent Dental Caries

Systematic Approach to Identify Novel Antimicrobial and Antibiofilm Molecules from Plants' Extracts and Fractions to Prevent Dental Caries

Published on: March 31, 2021

Area of Science:

Dental Public Health
Cariology
Epidemiology

Background:

Analysis of decayed, missing, and filled (DMF) rates in Norway over 30 years.
Identified a marked reduction in restoration needs linked to fluoride therapy and revised treatment criteria.

Purpose of the Study:

To analyze trends in DMF rates and caries treatment in Norway.
To evaluate the impact of preventive strategies and changing restoration criteria on dental health outcomes.

Main Methods:

Reviewed independent, cross-sectional DMF studies of young adults (1973-2006) and adolescents (1979-1996).
Utilized standardized methods, clinical records, and bitewing radiographs to assess caries progression and treatment.

Main Results:

Observed a significant reduction in mean decayed, missing, and filled surface (DMFS) scores from 1973-2006.
Noted a marked decrease in caries treatment, particularly after the mid-1990s, with significant changes in adolescent data attributed to altered treatment criteria in the 1980s.

Conclusions:

Active caries prevention and conservative restoration criteria effectively reduce the need for dental restorations.
Findings support a shift towards preventive care and judicious restorative treatment in dental practice.