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Cancer Survival Analysis01:21

Cancer Survival Analysis

Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
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Cancer Prevention02:59

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Related Experiment Video

Updated: Jul 5, 2026

A Bioluminescent and Fluorescent Orthotopic Syngeneic Murine Model of Androgen-dependent and Castration-resistant Prostate Cancer
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A Bioluminescent and Fluorescent Orthotopic Syngeneic Murine Model of Androgen-dependent and Castration-resistant Prostate Cancer

Published on: March 6, 2018

Recent trends in prostate cancer mortality show a continuous decrease in several countries.

Christine Bouchardy1, Gerald Fioretta1, Elisabetta Rapiti1

  • 1Geneva Cancer Registry, Institute for Social and Preventive Medicine, University of Geneva, Geneva, Switzerland.

International Journal of Cancer
|May 3, 2008
PubMed
Summary
This summary is machine-generated.

Prostate specific antigen (PSA) screening shows potential for reducing prostate cancer mortality. Analysis of 38 countries indicates declining mortality rates in some nations following PSA screening introduction.

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miRNA Expression Analyses in Prostate Cancer Clinical Tissues
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miRNA Expression Analyses in Prostate Cancer Clinical Tissues

Published on: September 8, 2015

Area of Science:

  • Oncology
  • Public Health
  • Epidemiology

Background:

  • Prostate specific antigen (PSA) screening aims to detect prostate cancer early and lower mortality.
  • Assessing PSA screening efficacy relies on monitoring prostate cancer mortality trends in the absence of definitive clinical trial data.

Purpose of the Study:

  • To analyze recent prostate cancer mortality trends across 38 countries.
  • To evaluate the potential impact of PSA screening on prostate cancer mortality rates.

Main Methods:

  • Utilized the IARC-WHO cancer mortality database.
  • Employed joinpoint analysis to examine prostate cancer mortality trends.
  • Identified distinct patterns in mortality trends across different countries.

Main Results:

  • In the USA and several European countries, prostate cancer mortality decreased to levels below pre-PSA screening introduction.
  • In Australia, New Zealand, and other European nations, mortality declined but remained above pre-screening levels.
  • Mortality rates continued to rise in several Eastern European, Latin American, and Asian countries.

Conclusions:

  • Observed trends in prostate cancer mortality suggest that PSA screening may contribute to reduced mortality.
  • The effectiveness of PSA screening varies geographically, with notable decreases in some high-income countries.
  • Further research and clinical trials are needed to definitively establish the impact of PSA screening on prostate cancer mortality.