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Rapid, Safe, and Simple Manual Bedside Nucleic Acid Extraction for the Detection of Virus in Whole Blood Samples
Published on: June 30, 2018
Nanoceramics for blood-borne virus removal
Yufeng Zhao1, Sadahiro Sugiyama, Thomas Miller
1Centre for Material and Fiber Innovation, Deakin University, Geelong Campus, Victoria 3217, Australia. fzhao@deakin.edu.au
Expert Review of Medical Devices
|May 3, 2008
Summary
Nanoceramics offer new virus removal methods for blood. While effective for free viruses, current nanoporous filter technology has limitations in capturing all viral forms.
Area of Science:
- Nanoscience and Nanotechnology
- Materials Science
- Biotechnology
Background:
- Advancements in nanoscience and nanotechnology have opened new avenues for developing effective virus-removal techniques.
- Nanoceramics, including nanostructured alumina, titania, and zirconia, are being explored for virus separation applications.
Purpose of the Study:
- To explore the potential of nanoceramics in developing efficient virus-removal systems.
- To evaluate the application of nanoceramic membranes, nanofibers, and nanoparticles for virus removal from blood.
Main Methods:
- Utilizing nanoporous/mesoporous ceramic membranes, ceramic nanofibers, and ceramic nanoparticles for virus filtration and adsorption.
- Investigating the chemical and thermal stability of nanoceramic materials for blood purification.
Main Results:
- Nanoceramic filtration and adsorption show promise for efficient virus removal from blood.
- Commercialized nanoceramic membranes and filters (e.g., sol-gel alumina, NanoCeram nanofiber filters) are already in use for blood virus removal.
- Current nanoporous filter technology is primarily effective for removing free viruses in the bloodstream.
Conclusions:
- Nanoceramics present a viable approach for developing stable and efficient virus removal systems.
- Further research is needed to overcome limitations in capturing all viral forms, particularly those associated with cells or in complex matrices.

