[Effect of fluoride on occurrence of degenerative changes in the spine and joints]

The occurrence of the degenerative changes of the hip, knee, elbow and spine was assessed in 1598 aluminium workers. Their average age was 43.1 years and the period of fluoride intoxication was average 17.0 years. The aging process was found to be predominant factor in the development of degenerative changes. An increased prevalence of changes was found in workers with the higher exposure to fluoride. Fluoride was assumed to be one of the factors causing degenerative changes of joints.