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Infective endocarditis caused by Staphylococcus aureus in a patient with atopic dermatitis: a case report

Gadha Mohiyiddeen1, Ian Brett, Edward Jude

  • 1Department of Medicine and Department of Radiology, Tameside General Hospital, Lancashire, UK. gaadha@yahoo.com

Journal of Medical Case Reports
|May 6, 2008
PubMed

Insights

Severe atopic dermatitis (AD) increases the risk of Staphylococcus aureus infections. This case highlights the potential for severe AD patients to develop life-threatening conditions like staphylococcal endocarditis.

Area of Science:

  • Dermatology
  • Infectious Diseases
  • Cardiology

Background:

  • Atopic dermatitis (AD) is prevalent in the UK, affecting all age groups.
  • Patients with AD frequently exhibit skin colonization by Staphylococcus aureus (S. aureus).
  • Severe AD poses a risk for invasive S. aureus infections, including bacteremia and endocarditis.

Purpose of the Study:

  • To report a case of acute endocarditis in a patient with severe atopic dermatitis.
  • To emphasize the link between severe AD and S. aureus-related invasive infections.

Main Methods:

  • Case report of a 30-year-old male with severe AD.
  • Management included intensive antibiotic therapy and surgical mitral valve replacement.
  • Concurrent treatment focused on managing the patient's severe atopic dermatitis.

Main Results:

  • The patient presented with acute endocarditis and significant mitral valve destruction due to S. aureus.
  • Successful treatment involved antibiotics, mitral valve replacement, and AD management.
  • The case demonstrates a severe complication of S. aureus infection in the context of AD.

Conclusions:

  • Severe atopic dermatitis is associated with an elevated risk of staphylococcal bacteremia and endocarditis.
  • Staphylococcal endocarditis should be considered in the differential diagnosis of febrile illnesses in patients with uncontrolled severe AD.
Abstract

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