Angiolymphoid hyperplasia involving large arteries

Area of Science:

• Vascular pathology
• Dermatology
• Surgical oncology

Background:

• Angiolymphoid hyperplasia with eosinophilia (ALHE) is a rare vascular proliferative disorder.
• It typically affects the skin of the head and neck.
• Noncutaneous localizations are uncommon, and arterial involvement is exceptionally rare.

Observation:

• This report details two rare cases of ALHE.
• The cases presented as pulsatile masses originating from the occipital and brachial arteries.
• These findings highlight an unusual manifestation of ALHE.

Findings:

• ALHE can present as primary masses in large peripheral arteries.
• The clinical presentation included pulsatile masses, mimicking other arterial pathologies.
• Histopathological confirmation is essential for diagnosis.

Implications:

• ALHE should be included in the differential diagnosis for peripheral arterial masses, especially in young patients.
• Early consideration of ALHE can lead to timely diagnosis and appropriate management.
• This expands the known spectrum of ALHE presentations, emphasizing the need for broader diagnostic considerations.