Related Experiment Video
Updated: Jul 5, 2026

08:49
External Cephalic Version: Is it an Effective and Safe Procedure?
Published on: June 6, 2020
Neonatal morbidity and mortality after elective cesarean delivery
Caroline Signore1, Mark Klebanoff
1Pregnancy and Perinatology Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA. signorec@mail.NIH.gov
Clinics in Perinatology
|May 6, 2008
Summary
Elective cesarean delivery (ECD) at term shows mixed neonatal outcomes. While potentially reducing some injuries, ECD may increase respiratory issues and mortality risks, necessitating careful consideration of benefits versus risks.
Area of Science:
- Obstetrics and Gynecology
- Neonatal Health
Background:
- Elective cesarean delivery (ECD) is increasingly common.
- Evidence on its impact on neonatal outcomes compared to vaginal birth is debated.
Purpose of the Study:
- To explore the effects of term elective cesarean delivery on neonatal morbidity and mortality.
- To evaluate the comparative safety of planned ECD versus planned vaginal delivery.
Main Methods:
- Review of available data on neonatal outcomes following elective cesarean delivery.
- Analysis of risks and benefits associated with planned cesarean versus planned vaginal birth.
Main Results:
- Data limitations prevent conclusive evidence on ECD safety.
- Some studies link ECD to increased neonatal respiratory morbidity and lacerations.
- Potential for decreased central and peripheral nervous system injury with ECD.
- Possible increased neonatal mortality risk with ECD, counterbalanced by reduced fetal demise risk in ongoing pregnancies.
Conclusions:
- Current data are insufficient to definitively recommend planned ECD over planned vaginal delivery.
- Patients and clinicians must weigh the competing risks and benefits of ECD.
- Further research is crucial to inform clinical decision-making regarding elective cesarean delivery.
Related Concept Videos
Development of the Oral Microbiota
The establishment of the oral microbiome begins before birth, challenging the long-held belief that the fetal oral cavity is sterile. The presence of oral microbes such as Streptococcus and Fusobacterium in amniotic fluid suggests that microbial exposure may occur in utero, potentially through translocation from the maternal oral or gastrointestinal tract. This early colonization primes the neonatal immune system and sets the stage for subsequent microbial succession. Maternal health,...
Teratogenicity
The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...

