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Transfusion in the newborn.

Sunarto1

  • 1Child Health Department Faculty of Medicine, Gadjah Mada University.

Paediatrica Indonesiana
|November 1, 1991
PubMed
Summary
This summary is machine-generated.

Neonatal intensive care often requires blood transfusions. Citrated blood is preferred over heparinized blood, with transfusions carefully considered for optimal outcomes.

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Area of Science:

  • Neonatal Medicine
  • Hematology
  • Transfusion Medicine

Background:

  • Blood transfusions are common in neonatal intensive care units (NICUs).
  • Careful consideration of transfusion type and indication is crucial for neonates.
  • Understanding the specific needs for whole blood versus blood components is essential.

Purpose of the Study:

  • To outline the indications for whole blood and blood component transfusions in neonates.
  • To emphasize the importance of rational transfusion practices in neonatal care.
  • To highlight preferred anticoagulants for neonatal transfusions.

Main Methods:

  • Review of current transfusion guidelines and practices in neonatal care.
  • Analysis of indications for whole blood transfusions.

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  • Analysis of indications for blood component transfusions.

    • Main Results:

    • Citrated blood is the preferred anticoagulant over heparinized blood for neonatal transfusions.
    • Whole blood is indicated for volume replacement, exchange transfusions, and when specific components are unavailable.
    • Blood components are indicated for improving oxygen-carrying capacity, managing coagulation defects, treating thrombocytopenic bleeding, and addressing gram-negative septicemia.

    Conclusions:

    • Rational use of whole blood and blood components optimizes therapeutic effects while minimizing adverse events in neonates.
    • Choosing the correct transfusion strategy is vital for improving neonatal outcomes.
    • Standardizing transfusion practices with preferred anticoagulants enhances safety and efficacy.