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Updated: Jul 5, 2026

Determining Immune System Suppression versus CNS Protection for Pharmacological Interventions in Autoimmune Demyelination
Published on: September 12, 2016
Boosting controlled autoimmunity: a new therapeutic target for CNS disorders
Diana García del Barco1, Jorge Berlanga, Eduardo Penton
1Center for Genetic Engineering & Biotechnology, Avenue 31 e/158 & 190, PO Box 6162, Cubancan, Playa 10600, Havana City, Cuba. diana.garcia@cigb.edu.cu
Abstract:
In most tissues, the immune system plays an essential role in protection, repair and healing. Although immunologically privileged, the CNS remains subject to a highly regulated form of immunosurveillance that is of increasing interest. There is evolving evidence that repair mechanisms within the CNS may be enhanced by exploiting an innate process of protective immunity. Understanding the regulation of protective autoimmunity within the CNS is likely to lead to novel therapeutic approaches to neuroinflammatory and neurodegenerative diseases.
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