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Iron deficiency in young Lebanese children: association with elevated blood lead levels
Samar Muwakkit1, Iman Nuwayhid, Mona Nabulsi
1Department of Pediatrics, Division of Hematology Oncology, American University of Beirut Medical Center, Beirut, Lebanon. sm03@aub.edu.lb
Insights
Iron-deficiency anemia (IDA) and low transferrin saturation (TS) are prevalent in Lebanese children, linked to lead exposure and lack of iron supplements. These conditions require national interventions, including iron fortification and lead exposure control.
Area of Science:
- Pediatric Nutrition
- Environmental Health
- Hematology
Background:
- Iron-deficiency anemia (IDA) and low transferrin saturation (TS) are significant public health concerns in pediatric populations.
- Understanding the prevalence and risk factors for IDA and TS <12% in specific regions is crucial for targeted interventions.
Purpose of the Study:
- To determine the prevalence of TS <12% and IDA in Lebanese children.
- To investigate the association of TS <12% and IDA with dietary habits, sociodemographic factors, and blood lead levels.
Main Methods:
- A cross-sectional study involving 268 children aged 11–75 months in Lebanon.
- Data collection included nutritional status, blood counts, transferrin saturation (TS), and blood lead levels.
- Statistical analysis was performed to identify associations between variables.
Main Results:
- The prevalence of TS <12% was 33.6% and IDA was 20.5%.
- Both conditions were associated with not receiving iron supplements and higher blood lead levels, particularly in younger children (11–23 months).
- IDA was more common in males.
Conclusions:
- IDA is common among Lebanese children and is linked to elevated blood lead levels and insufficient iron supplementation.
- Cultural dietary practices may also contribute to iron deficiency.
- National strategies including iron fortification and lead exposure reduction are recommended.
Objective:
To measure the prevalence of transferrin saturation (TS) <12%, and iron-deficiency anemia (IDA) in Lebanese children, and their association with dietary habits, sociodemographic characteristics, and blood lead levels.
Procedure:
A cross-sectional study was performed over a period of 2 years. Of 268 children studied, 142 (53%) were boys and 126 (47%) were girls with an age range of 11 to 75 months. Information collected included nutritional status, blood counts, TS, and blood lead levels.
Results:
The total prevalence of TS<12% and IDA were 33.6% and 20.5%, respectively, and were associated with not having received iron supplements. IDA was more prevalent among males (P=0.04). TS<12% and IDA were significantly associated with elevated blood lead levels in the first age group (11 to 23 mo) (P=0.04, odds ratio=3.19) and (P=0.006, odds ratio=4.59), respectively.
Conclusions:
IDA is common in Lebanese children and is associated with increased blood lead levels, lack of iron supplementation, and cultural dietary habits. Remedial measures such as iron fortification of commonly consumed food are needed on the national level. Lead exposure must be controlled and awareness must be raised about the potentially devastating consequences of combined iron deficiency and lead poisoning on young children.
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