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The case for common reference intervals
Graham R D Jones1, Antony Barker, Jill Tate
1Department of Chemical Pathology, St Vincent's Hospital, Faculty of Medicine, University of NSW, Sydney, NSW, Australia. gjones@stvincents.com.au
Insights
Laboratories should adopt common pathology reference intervals across Australia and New Zealand. This standardization improves healthcare integration and reduces costs, benefiting the medical community.
Area of Science:
- Clinical Pathology
- Laboratory Medicine
- Health Informatics
Background:
- Current pathology reference intervals are laboratory-specific, leading to inconsistencies.
- This fragmented approach hinders the integration of electronic health information.
- Existing methods are often poorly executed and costly.
Purpose of the Study:
- To advocate for the adoption of common reference intervals in pathology.
- To promote standardized reporting formats and assay standardization.
- To address the challenges of modern healthcare with unified pathology data.
Main Methods:
- This study presents a conceptual argument and proposes a shift in practice.
- It emphasizes the need for collaboration across laboratories in Australia and New Zealand.
- The focus is on the feasibility and benefits of standardization.
Main Results:
- Implementing common reference intervals offers a more effective approach than current practices.
- Standardization can lead to improved data integration and potentially reduced costs.
- A unified system better serves the evolving needs of the medical community.
Conclusions:
- A move towards common pathology reference intervals is essential for modern healthcare.
- Standardization is technically achievable and crucial for the pathology profession.
- Failure to standardize represents a missed opportunity to meet contemporary health challenges.
Abstract:
The current paradigm for pathology reference intervals is for each laboratory to determine its own interval for use with each test offered by the laboratory. It is our contention that this approach does not best serve the medical community, especially at a time when electronic databases of health information are being expanded and integrated. We also believe that this approach is not performed well in many laboratories and is excessively expensive in practice. In contrast, we believe that the preferable option is to develop and apply common reference intervals throughout Australia and New Zealand, together with common reporting formats and assay standardisation wherever this is possible. We are aware that these are neither trivial nor simple issues, however we believe that failure to achieve this goal where technically possible will be a failure of the pathology profession to meet the challenges of the modern health community.
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