Related Experiment Video
Updated: Jul 5, 2026

Utilizing Percutaneous Ventricular Assist Devices in Acute Myocardial Infarction Complicated by Cardiogenic Shock
Published on: June 12, 2021
Percutaneous coronary intervention in a patient with acute ST-elevation myocardial infarction and hemophilia A
David Quintero1, Mazda Biria, David G Meyers
1Division of Cardiovascular Medicine, Department of Internal Medicine, The University of Kansas School of Medicine, Kansas University Medical Center, Kansas City, KS, 66160, USA.
Insights
This study presents a rare case of heart attack in a hemophilia patient, successfully treated with coronary stenting. The patient remained free of complications for two years, highlighting new treatment possibilities.
Area of Science:
- Cardiology
- Hematology
Background:
- Myocardial infarction (MI) is rare in hemophilia patients.
- Managing anticoagulation and platelet inhibition is challenging in hemophilia due to bleeding risks.
Observation:
- This report details the first MI case in a hemophilia patient not directly caused by clotting factor infusion.
- The patient underwent primary coronary artery stenting, a procedure rarely performed in this population.
Findings:
- The patient experienced no ischemic or bleeding complications at two years post-MI and stenting.
- Successful management of a myocardial infarction in a hemophilia patient was achieved without exacerbating bleeding issues.
Implications:
- This case suggests that coronary artery stenting can be a viable treatment option for myocardial infarction in hemophilia patients.
- Further research is warranted to establish optimal antithrombotic strategies for hemophilia patients with acute coronary syndromes.
Abstract:
We report the first case of myocardial infarction in a hemophilia patient which was not directly precipitated by infusion of a clotting factor, and the second hemophilia patient with infarction treated with primary coronary artery stenting. Anticoagulation and platelet inhibition are problematic in such patients. At 2 years after infarction, our patient has experienced neither ischemic nor bleeding complications.
Related Concept Videos
Anticoagulant Drugs: Low-Molecular-Weight Heparins
Acute Coronary Syndrome I: Introduction
Acute Coronary Syndrome IV: Interprofessional Care
Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care
Venous Thrombosis III: Interprofessional Care
Introduction to Hemostasis
The three phases of hemostasis involve many clotting factors present in plasma and several substances released by platelets and injured tissue cells. It is a fast, localized, and...

