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Updated: Jul 5, 2026

Collecting Sleep, Circadian, Fatigue, and Performance Data in Complex Operational Environments

Collecting Sleep, Circadian, Fatigue, and Performance Data in Complex Operational Environments

Published on: August 8, 2019

Aging, circadian weight change, and nocturia.

¹Faculty of Medicine, McGill University, Montreal, Que., Canada. mkaye@videotron.ca

Nephron. Physiology

|May 8, 2008

Summary

Nocturia in older adults is caused by daytime salt and water retention, leading to increased body weight overnight. This condition can be managed with diuretics or daytime rest.

Area of Science:

Nephrology
Gerontology
Circadian Rhythms

Background:

Young individuals excrete more sodium during the day, while older adults with nocturia show the opposite pattern.
The underlying cause of nocturia in older populations remains unclear.

Purpose of the Study:

To investigate the physiological mechanisms behind nocturia in older adults.
To determine the relationship between daytime fluid retention and nighttime urination.

Main Methods:

A self-study assessed weight changes and urine output during day and night, with interventions including diuretics and recumbency.
A community study measured circadian weight changes and nocturia in 102 individuals.
Urine electrolytes and weight changes were compared between nocturic and non-nocturic older adults.

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Collecting Sleep, Circadian, Fatigue, and Performance Data in Complex Operational Environments

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Through-the-Wall Blood Sampling Method to Minimize Sleep Disruption in Clinical Settings

Through-the-Wall Blood Sampling Method to Minimize Sleep Disruption in Clinical Settings

Published on: June 13, 2025

Main Results:

Salt and water are retained during the day, leading to natriuresis and diuresis overnight.
Nocturia correlates with greater overnight weight gain.
Administering a diuretic in the afternoon or adopting daytime recumbency prevented nocturia.

Conclusions:

Idiopathic nocturia in older adults stems from daytime volume expansion, exacerbated by the upright posture.
This is hypothesized to involve sodium retention via sympathetic renal nerve activity and angiotensin II, increasing sodium reabsorption or reducing glomerular filtration rate.