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Updated: Jul 5, 2026

A High-Throughput Multiplexed Screening for Type 1 Diabetes, Celiac Diseases, and COVID-19
Published on: July 5, 2022
[Examples of screening investigations]
A Eickhoff1, A Hahn, J F Riemann
1Medizinische Klinik C, Klinikum der Stadt Ludwigshafen gGmbH, Bremserstrasse 79, 67063, Ludwigshafen, Germany. eickhofa@klilu.de
Secondary cancer prevention, including screening for breast, prostate, and colorectal cancers (CRC), is crucial due to limited primary prevention uptake. Current screening rates remain suboptimal, highlighting a need for improved adherence to established guidelines for early cancer detection.
Area of Science:
- Oncology
- Public Health
- Preventive Medicine
Context:
- Limited public acceptance of primary cancer prevention strategies necessitates a focus on secondary prevention.
- High mortality and socio-economic burden associated with breast, prostate, and colorectal cancer (CRC) underscore the importance of early detection.
- Despite established screening protocols, adherence rates for secondary cancer prevention measures hover around 30-40%.
Purpose:
- To highlight the critical role of secondary cancer prevention in mitigating the impact of high-incidence cancers.
- To review current screening guidelines and implementation status for breast, prostate, and colorectal cancers.
- To identify gaps in current cancer screening programs, such as the exclusion of PSA testing.
Summary:
- Effective and accessible screening tests exist for common cancers like breast, prostate, and CRC.
- Established screening programs include ileocoloscopy for CRC (over 55), fecal occult blood testing (FOBT) for CRC (over 50), and mammography for breast cancer (women 50-69).
- Annual examinations for prostate cancer are available for men over 45, but Prostate-Specific Antigen (PSA) testing is not yet included.
Impact:
- Improving adherence to secondary prevention guidelines can significantly reduce cancer mortality and treatment costs.
- Timely implementation of screening programs across all federal states is essential for widespread early cancer detection.
- Integrating tests like PSA into routine screening could further enhance early detection and management of prostate cancer.
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