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Evidence for cyclic AMP-dependent protein kinase activity in isolated guinea pig and rat liver mitochondria

B Kleitke, H Sydow, A Wollenberger

Acta Biologica Et Medica Germanica

|January 1, 1976

Abstract:

Purified preparations of guinea pig and rat liver mitochondria contain considerable latent cAMP-dependent protein kinase activity that is revealed by treatment with 1% Triton X-100. The solubilized kinase was partly purified by DEAE-cellulose chromatography. It accepts protein in the washed Triton-extracted mitochondria as substrate.

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