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Related Concept Videos

Econometric Views (EViews)01:29

Econometric Views (EViews)

Econometric Views, often stylized as EViews, is a package that merges statistical analysis with econometric studies. It is designed to provide tools for time series analysis, forecasting, and econometric model simulation. The software originated from MicroTSP software and has evolved significantly since its inception in 1981. The history of EViews is marked by a continuous effort to enhance its computational speed and user interface. It was initially developed for large computing systems but...
Stability of structures01:14

Stability of structures

In mechanical engineering, the stability of systems under various forces is critical for designing durable and efficient structures. One fundamental way to explore these concepts is by analyzing systems like two rods connected at a pivot point, O, with a torsional spring of spring constant k at the pivot point. This system is similar in appearance to a scissor jack used to change tires on a car. In this case, the arms of the linkage (equivalent to the rods in this system) are entirely vertical,...
Pole and System Stability01:24

Pole and System Stability

The transfer function is a fundamental concept representing the ratio of two polynomials. The numerator and denominator encapsulate the system's dynamics. The zeros and poles of this transfer function are critical in determining the system's behavior and stability.
Simple poles are unique roots of the denominator polynomial. Each simple pole corresponds to a distinct solution to the system's characteristic equation, typically resulting in exponential decay terms in the system's response.
Stability of Equilibrium Configuration01:23

Stability of Equilibrium Configuration

Understanding the stability of equilibrium configurations is a fundamental part of mechanical engineering. In any system, there are three distinct types of equilibrium: stable, neutral, and unstable.
A stable equilibrium occurs when a system tends to return to its original position when given a small displacement, and the potential energy is at its minimum. An example of a stable equilibrium is when a cantilever beam is fixed at one end and a weight is attached to the other end. If the weight...
Stability01:28

Stability

The time response of a linear time-invariant (LTI) system can be divided into transient and steady-state responses. The transient response represents the system's initial reaction to a change in input and diminishes to zero over time. In contrast, the steady-state response is the behavior that persists after the transient effects have faded.
The stability of an LTI system is determined by the roots of its characteristic equation, known as poles. A system is stable if it produces a bounded...
Quantitative Analysis01:12

Quantitative Analysis

Quantitative analysis is a technique for measuring the amount of specific constituents in a sample. When the sample's composition is unknown, qualitative analysis is performed first to identify its components, which ensures that the correct substances are measured during the quantitative phase.
In quantitative analysis, two key measurements are made: the sample quantity and a property proportional to the amount of the analyte (the substance being analyzed). This forms the basis of the method...

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Related Experiment Video

Updated: Jul 5, 2026

Evaluating Postural Control and Lower-extremity Muscle Activation in Individuals with Chronic Ankle Instability
07:52

Evaluating Postural Control and Lower-extremity Muscle Activation in Individuals with Chronic Ankle Instability

Published on: September 18, 2020

OREST: the online resource for EST analysis.

Brigitte Waegele1, Thorsten Schmidt, H Werner Mewes

  • 1Institute for Bioinformatics and Systems Biology (MIPS), Helmholtz Zentrum München - German Research Center for Environmental Health (GmbH), Ingolstädter Landstrasse 1, D-85764 Neuherberg, Germany. brigitte.waegele@helmholtz-muenchen.de

Nucleic Acids Research
|May 9, 2008
PubMed
Summary
This summary is machine-generated.

OREST is a powerful tool for analyzing expressed sequence tag (EST) data, especially when genome sequences are unavailable. It aids in gene identification, functional annotation, and disease association, improving data recovery by 13%.

Related Experiment Videos

Last Updated: Jul 5, 2026

Evaluating Postural Control and Lower-extremity Muscle Activation in Individuals with Chronic Ankle Instability
07:52

Evaluating Postural Control and Lower-extremity Muscle Activation in Individuals with Chronic Ankle Instability

Published on: September 18, 2020

Area of Science:

  • Bioinformatics
  • Genomics
  • Molecular Biology

Background:

  • Expressed Sequence Tag (EST) libraries provide an economical method for studying organisms lacking complete genome sequences.
  • Rapid analysis of large EST datasets is crucial for understanding gene expression and function.

Purpose of the Study:

  • To introduce OREST, a server-based pipeline for rapid EST and cDNA analysis in mammals and fungi.
  • To enhance the recovery and functional characterization of EST data through genome mapping and annotation.

Main Methods:

  • OREST maps DNA sequences to reference gene products and complete genomes, recovering an additional 13% of EST data.
  • Functional annotation is performed using the FunCat scheme and Gene Ontology (GO) terms.
  • Disease association is predicted using the Morbid Map (OMIM) classification.
  • PROMPT software enables statistical analysis of annotation terms for enrichment and depletion.

Main Results:

  • OREST successfully identified and functionally characterized over 3000 EST sequences from the common marmoset monkey (Callithrix jacchus).
  • Genome mapping significantly increased the proportion of analyzable EST data.

Conclusions:

  • OREST is an effective pipeline for comprehensive EST analysis, facilitating gene discovery and functional insights.
  • The pipeline aids in understanding gene function, disease associations, and provides statistical analysis for biological datasets.