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Diagnosis and Surgical Treatment of Human Brucellar Spondylodiscitis
Published on: May 23, 2021
Salmonella spondylodiscitis associated with a mycotic abdominal aortic aneurysm and paravertebral abscess
Thomas J Learch1, Brian Sakamoto, Amy C Ling
1Radiology, S. Mark Taper Foundation Imaging Center, Cedars-Sinai Medical Center, 8700 Beverly Blvd., Suite M-335, Los Angeles, CA 90048, USA. thomas.learch@cshs.org
Abstract:
Each year, 1.4 million people in the United States are infected with Salmonella (Beneson et al. [23] Am J Med, 110:60-63, 2001). The most common clinical presentation of Salmonella infection is gastroenteritis which is usually self-limited, lasting between one to four days (Black et al. [24] N Engl J Med, 261:811-816, 1960). Although most infections are mild-to-moderate, serious disease, and death does occur (Voetsch et al. [25] CID, 38:S127-S132, 2004). A rare but increasing number of patients present with Salmonellosis spondylodiscitis resulting from contiguous spread of infection from the adjacent abdominal aorta. Concurrent infection of these structures exacerbates morbidity, necessitating an elevated clinical suspicion in patients with appropriate risk factors, clinical signs and symptoms. Furthermore, an overall mortality rate of 67% makes mycotic abdominal aortic aneurysms highly lethal (Gonda et al. [26] Radiology, 168:343-346, 1988). Thus, early diagnosis is crucial, allowing for prompt antibiotic and surgical management. Laboratory and imaging tests obtained at the initial suspicion for infection of the spine and aorta facilitates diagnosis while minimizing or preventing more serious complications like paresis and aortic rupture. We present a patient with a mycotic abdominal aortic aneurysm infected with Salmonella enteritides that spread to the adjacent lumbar vertebra and left psoas muscle.
Insights
Salmonella infection can spread to the aorta, causing a rare but deadly condition called a mycotic abdominal aortic aneurysm. Early diagnosis and treatment are crucial for survival.
Area of Science:
- Infectious Diseases
- Vascular Surgery
- Radiology
Background:
- Salmonella infections commonly cause gastroenteritis but can lead to severe systemic disease.
- Mycotic abdominal aortic aneurysms (MAAAs) are rare, life-threatening infections of the aorta.
- MAAAs can result from contiguous spread of infection from adjacent structures.
Observation:
- A rare case of Salmonellosis spondylodiscitis is presented, originating from an infected abdominal aorta.
- The patient had a mycotic abdominal aortic aneurysm caused by Salmonella enteritidis.
- Infection spread contiguously to the lumbar vertebra and psoas muscle.
Findings:
- Concurrent infection of the aorta and spine significantly increases morbidity and mortality.
- Mycotic abdominal aortic aneurysms have a high mortality rate (67%).
- Prompt diagnosis via laboratory and imaging is essential for effective management.
Implications:
- Elevated clinical suspicion is necessary for patients with risk factors for Salmonella-related MAAA.
- Early diagnosis and treatment, including antibiotics and surgery, can prevent severe complications.
- This case highlights the importance of considering Salmonella as a pathogen in spinal and aortic infections.
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