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Applications of Liquid-Chromatography Tandem Mass Spectrometry in Natural Products Research: Tropane Alkaloids as a Case Study
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Dammarane- and taraxastane-type triterpenoids from Saussurea oligantha Franch
Xue-Hu Li1, Huan-Yang Qi, Yan-Ping Shi
1Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou, China.
Abstract:
A new dammarane triterpenoid oliganthas A (1) and a new taraxastane triterpenoid oliganthas B (2), as well as five known taraxastane triterpenoids, ptiloepoxide (3), taraxast-20(30)ene-3beta,21alpha-diol (4), 22-oxo-20-taraxasten-3beta-ol (5), taraxast-20-ene-3beta,30-diol (6), and taraxastane-3beta,20alpha-diol (7), were isolated from the whole plant of Saussurea oligantha Franch. Their structures were elucidated by a series of spectroscopic methods. These compounds, especially taraxastanes 2, 5, and 6, exhibited significant antibacterial activity against Actinomyces viscosus ATCC27044.
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