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Related Concept Videos

Arboviral Encephalitis01:25

Arboviral Encephalitis

Arboviral encephalitis refers to brain inflammation caused by arthropod-borne viruses, particularly those transmitted through mosquito vectors. Among these, West Nile virus (WNV), a member of the Flaviviridae family, is a significant public health concern. WNV is an enveloped, positive-sense, single-stranded RNA virus. Human infection typically begins when an infected mosquito introduces the virus into the dermis during feeding. The primary transmission cycle involves birds as amplifying hosts...
Glaucoma: Overview01:25

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
Encephalitis ll: Pathophysiology01:26

Encephalitis ll: Pathophysiology

Encephalitis is inflammation of the brain parenchyma caused by direct viral invasion or immune-mediated mechanisms triggered by infections or tumors. Both processes lead to neuronal injury, disrupted neurotransmission, and diverse neurological symptoms, often with overlapping clinical and pathological features.Autoimmune EncephalitisIn autoimmune encephalitis, antibodies target neuronal antigens on cell surfaces, synapses, or within neurons. A key example is anti-NMDAR encephalitis, which can...
Yellow Fever01:18

Yellow Fever

Yellow fever is a viral hemorrhagic disease caused by the yellow fever virus (YFV), a member of the Flaviviridae family. It is transmitted primarily by Aedes and Haemagogus mosquitoes in tropical and subtropical regions of Africa and South America. After transmission through a mosquito bite, the virus initially replicates in skin-resident immune cells such as dendritic cells and macrophages. These cells then migrate to the lymph nodes, where viral replication increases, eventually leading to...
Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
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Encephalitis l: Introduction

Encephalitis is inflammation of the brain parenchyma, most often due to infections or autoimmune processes. It presents with neuropsychiatric features such as fever, altered mental status, behavioral changes, cognitive dysfunction, seizures, focal deficits, and sometimes autonomic instability. In some cases, the meninges are also involved, resulting in meningoencephalitis.Infectious CausesInfectious encephalitis is most commonly viral but can also result from bacterial, fungal, or parasitic...

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Related Experiment Video

Updated: Jul 5, 2026

A Murine Model of Dengue Virus-induced Acute Viral Encephalitis-like Disease
04:23

A Murine Model of Dengue Virus-induced Acute Viral Encephalitis-like Disease

Published on: April 28, 2019

Uveitis following dengue fever.

A Gupta1, R Srinivasan, S Setia

  • 1Department of Ophthalmology and Biochemistry, Jawaharlal Institute of Postgraduate Medical Education and Research, Pondicherry University, Pondicherry, India.

Eye (London, England)
|May 10, 2008
PubMed
Summary

Delayed uveitis can occur months after dengue fever infection. This study found that prompt treatment with steroids led to good visual recovery in most patients with post-dengue uveitis.

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Area of Science:

  • Ophthalmology
  • Infectious Diseases
  • Virology

Background:

  • Dengue fever is a mosquito-borne viral illness with various systemic manifestations.
  • Ocular complications following dengue infection are uncommon.
  • Delayed onset of uveitis after dengue fever has been rarely reported.

Purpose of the Study:

  • To describe the occurrence and clinical characteristics of uveitis in patients with a history of dengue fever.
  • To evaluate the treatment outcomes and prognosis of post-dengue uveitis.

Main Methods:

  • A case series design was employed, including six patients who developed uveitis 3-5 months post-dengue infection.
  • Ocular symptoms were assessed, and patients were treated with topical/oral steroids, cycloplegics, and hypotensive agents as needed.
  • Follow-up ranged from 3-5 months to monitor treatment response and recurrence.

Main Results:

  • Six patients (seven eyes) presented with uveitis attributed to prior dengue fever.
  • Anterior uveitis was most common (6 eyes), with one case of severe vitritis.
  • All patients responded well to treatment, achieving visual acuity of 6/9 or better in most eyes.

Conclusions:

  • Uveitis is a rare but potential delayed ophthalmic complication of dengue fever.
  • Ophthalmologists should consider dengue fever in the differential diagnosis of uveitis, especially in endemic areas.
  • Post-dengue uveitis generally has a favorable prognosis with appropriate management.