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Updated: Jul 5, 2026
12:03
Antimicrobial Synergy Testing by the Inkjet Printer-assisted Automated Checkerboard Array and the Manual Time-kill Method
Published on: April 18, 2019
Biapenem American Cyanamid Co
1R W Johnson Pharmaceutical Research Institute, Welsh and McKean Roads, R-439, Spring House, PA 19477-0776, USA. SDax@prius.jnj.com
Idrugs : the Investigational Drugs Journal
|May 10, 2008
Summary
Biapenem is a broad-spectrum injectable carbapenem antibiotic. It is currently undergoing Phase III trials for skin infections in multiple countries and Phase I trials in the UK and US.
Area of Science:
- Pharmacology
- Microbiology
- Clinical Trials
Background:
- Biapenem is an injectable carbapenem antibiotic.
- It exhibits broad-spectrum activity against various bacteria.
- Lederle Japan, a joint venture between Cyanamid and Takeda, has submitted Biapenem for marketing approval in Japan.
Purpose of the Study:
- To evaluate the efficacy and safety of Biapenem.
- To assess Biapenem's potential for treating bacterial infections.
Main Methods:
- Biapenem is undergoing Phase III clinical trials for skin infections.
- Phase I trials are being conducted in the UK and US.
- The trials involve participants in Germany, South Africa, Spain, Australia, and New Zealand.
Main Results:
- Biapenem demonstrates broad-spectrum antibacterial activity.
- Clinical trials are progressing through Phase I and Phase III stages.
Conclusions:
- Biapenem shows promise as a broad-spectrum antibiotic.
- Further clinical evaluation is ongoing for various indications and geographical regions.
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