Related Experiment Video

Updated: Jul 5, 2026

Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform
07:13

Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform

Published on: April 12, 2021

Evaluation of the vaccination status in pediatric renal transplant recipients

T S S Chaves1, L M Pereira, S S De Santos

  • 1Division of Infectious and Parasitic Diseases, Hospital das Clínicas, University of São Paulo School of Medicine, São Paulo, Brazil.

Pediatric Transplantation
|May 10, 2008
PubMed

Insights

Pediatric kidney transplant patients in Brazil have poor vaccination coverage. Most children lack essential vaccines before and after transplantation, highlighting missed opportunities for immunization.

Area of Science:

  • Pediatric Nephrology
  • Immunology
  • Transplantation

Background:

  • Pediatric renal transplant recipients require specific vaccination protocols due to their immunocompromised state.
  • Inadequate immunization increases the risk of vaccine-preventable diseases in this vulnerable population.

Purpose of the Study:

  • To evaluate the immunization status of pediatric patients undergoing renal transplantation.
  • To identify gaps in vaccination coverage before and after transplantation.

Main Methods:

  • Retrospective analysis of vaccination charts for 46 pediatric patients (aged 1-18 years).
  • Assessment of immunization according to the Brazilian National Immunization Program and Special Immunobiological Agents Program.
  • Evaluation of vaccination status pre- and post-kidney transplantation.

Main Results:

  • Only 4.3% of patients had up-to-date vaccination records pre- and post-transplant.
  • While routine vaccines were often administered, special vaccines for immunocompromised children were frequently missed.
  • A significant proportion of patients (62.2% pre-transplant, 52.1% post-transplant) received only routine vaccines, not specialized ones.

Conclusions:

  • Pediatric renal transplant patients in Brazil exhibit incomplete immunization status.
  • Missed vaccination opportunities and apprehension contribute to suboptimal immunization coverage.
  • Improved vaccination strategies are crucial, particularly before kidney transplantation, for children with kidney diseases.

More Related Videos

Murine Renal Transplantation Procedure18:48

Murine Renal Transplantation Procedure

Published on: July 10, 2009

Related Concept Videos

Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
Kidney Transplant III: Nursing Management01:16

Kidney Transplant III: Nursing Management

Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...
Kidney Transplant II: Surgical Procedure01:26

Kidney Transplant II: Surgical Procedure

Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living donor...
Pharmacokinetics in Pediatric Patients: Drug Excretion01:26

Pharmacokinetics in Pediatric Patients: Drug Excretion

In pediatric medicine, understanding the renal function and drug elimination nuances is crucial for administering safe and effective treatments. Newborns, in particular, display markedly slower renal functions than adults, profoundly affecting how drugs are cleared from their bodies. This slower drug clearance requires clinicians to extend the dosing intervals for many medications to prevent drug accumulation and toxicity while ensuring therapeutic efficacy.One key area where these adjustments...
Acute Kidney Injury IV: Diagnostic Studies and Prevention01:30

Acute Kidney Injury IV: Diagnostic Studies and Prevention

Accurate diagnosis and effective prevention are critical in managing Acute Kidney Injury (AKI), which is linked to high mortality rates ranging from 10% to 80%. Timely recognition of at-risk patients and careful monitoring can significantly reduce the likelihood of kidney damage.Diagnostic Assessments:The diagnostic process starts with a comprehensive medical history to identify prerenal, intrarenal, and postrenal causes.Prerenal causes, such as dehydration, hypotension, or blood loss, should...
Continuous Renal Replacement Therapy01:30

Continuous Renal Replacement Therapy

Continuous Renal Replacement Therapy, also known as CRRT, is a procedural treatment for acute kidney injury (AKI) that gradually removes uremic toxins and fluids while maintaining acid-base balance and stabilizing electrolytes. It is particularly useful for hemodynamically unstable patients. Unlike intermittent hemodialysis, which is faster, CRRT provides a gentler approach over 24 hours, closely mimicking the function of natural kidneys. However, CRRT is not ideal for patients with...