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Multilocus analysis of GAW15 NARAC chromosome 18 case-control data

Sharon R Browning1, Jessica Thomas

  • 1Department of Statistics, The University of Auckland, Private Bag 92019, Auckland, New Zealand. browning@stat.auckland.ac.nz

BMC Proceedings
|May 10, 2008
PubMed

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Genome-wide Association Studies-GWAS

Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...