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Large-Scale Multi-Omics Genome-Wide Association Studies (Mo-GWAS): Guidelines for Sample Preparation and Normalization
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Functional group-based linkage analysis of gene expression trait loci

Na Li1, Baolin Wu, Peng Wei

  • 1Division of Biostatistics, University of Minnesota, A460 Mayo Building MMC 303, 420 Delaware Street Southeast, Minneapolis, Minnesota 55126, USA. nali@umn.edu

BMC Proceedings
|May 10, 2008
PubMed
Summary

This study investigates methods for linkage analysis using multiple gene expression traits. Principal-component analysis (PCA) showed stronger linkage evidence, while linear discriminant analysis (LDA) offered higher heritability for composite traits.

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