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Updated: Jul 5, 2026

A Pathway Association Study Tool for GWAS Analyses of Metabolic Pathway Information
Published on: July 1, 2020
Visualizing genotype x phenotype relationships in the GAW15 simulated data
Xuejun Qin1, Silke Schmidt, Eden Martin
1Center for Human Genetics, Duke University Medical Center, Durham, NC 27710, USA. xqin@chg.duhs.duke.edu
Abstract:
We have developed a graphical display tool called SIMLAPLOT for visualizing different ways in which continuous covariates may influence the genotype-specific risk for complex human diseases. The purpose of our study was to examine continuous covariates in the Genetic Analysis Workshop 15 simulated data set using our novel graphical display tool, with knowledge of the answers. The generated plots provide information about genetic models for the simulated continuous covariates and may help identify the single-nucleotide polymorphisms associated with the underlying quantitative trait loci.
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