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Related Concept Videos

Cholecystitis01:20

Cholecystitis

Cholecystitis is inflammation of the gallbladder, most commonly caused by obstruction of the cystic duct. This blockage prevents bile from draining, leading to gallbladder distension, inflammation, and potentially serious complications. This condition may present acutely or chronically and can happen with or without gallstones.EtiologyAbout 95% of cholecystitis cases are calculous, caused by gallstones blocking the cystic duct, leading to bile accumulation and inflammation of the gallbladder...
Gallbladder01:17

Gallbladder

The gallbladder is a small, pear-shaped organ that plays a crucial role in our digestive system. Measuring about 10 cm in length, it is comparable in size to a kiwi fruit and is located in a hollow area on the lower surface of the liver. The gallbladder's primary function is to store and concentrate bile, a fluid produced by the liver that aids in digestion.
The gallbladder's anatomy consists of three regions: the fundus, body, and neck. Extending from the neck, the cystic duct joins the common...
Diseases of the Liver and Gallbladder01:26

Diseases of the Liver and Gallbladder

Liver and gallbladder diseases are a significant health concern, with prominent conditions including cirrhosis, hepatitis, non-alcoholic fatty liver disease (NAFLD), and gallstones. Jaundice is a common manifestation of liver and biliary disease.
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not related to...

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Related Experiment Video

Updated: Jul 5, 2026

Complete Laparoscopic Radical Resection of Perihilar Cholangiocarcinoma Type IIIb
04:50

Complete Laparoscopic Radical Resection of Perihilar Cholangiocarcinoma Type IIIb

Published on: January 17, 2025

Gallbladder cancer.

Stavros Gourgiotis1, Hemant M Kocher, Leonardo Solaini

  • 1Second Surgical Department, 401 General Army Hospital of Athens, Athens, Greece. drsgourgiotis@tiscali.co.uk

American Journal of Surgery
|May 10, 2008
PubMed
Summary

Gallbladder cancer (GC) is a rare, lethal disease with unclear etiology and non-specific symptoms. Early detection and radical cholecystectomy offer the best prognosis, but are only possible in a minority of patients.

Related Experiment Videos

Last Updated: Jul 5, 2026

Complete Laparoscopic Radical Resection of Perihilar Cholangiocarcinoma Type IIIb
04:50

Complete Laparoscopic Radical Resection of Perihilar Cholangiocarcinoma Type IIIb

Published on: January 17, 2025

Area of Science:

  • Oncology
  • Gastroenterology

Background:

  • Gallbladder cancer (GC) is a rare but highly lethal neoplasm.
  • Understanding its epidemiology, etiology, pathology, and clinical presentation is crucial.

Purpose of the Study:

  • To review the epidemiology, etiology, pathology, symptoms, diagnosis, staging, treatment, and prognosis of gallbladder cancer.
  • To consolidate current knowledge on GC management and outcomes.

Main Methods:

  • A comprehensive literature search of the Pubmed database was conducted from 1971 to February 2007.
  • Articles were reviewed, and relevant references were extracted through hand-searching bibliographies.
  • The search was limited to English-language publications.

Main Results:

  • The precise etiology of GC remains undetermined, and its symptoms are often non-specific.
  • Radical cholecystectomy is potentially curative but feasible in only 10-30% of cases.
  • Re-resection is indicated for incidental GC except for T1a stage; advanced cases require palliative treatment. Laparoscopic cholecystectomy is contraindicated for GC.

Conclusions:

  • The overall prognosis for gallbladder cancer is extremely poor.
  • Surgical resection outcomes are being re-evaluated, while the efficacy of chemotherapy and radiotherapy remains debated.