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Published on: October 22, 2020
Smoking mentholated cigarettes impairs coronary microvascular function as severely as does smoking regular cigarettes
Ozgur Ciftci1, Semra Topcu, Mustafa Caliskan
1Department of Cardiology, Baskent University, Konya Teaching and Medical Research Center, Konya, Turkey. ozgurciftci@baskent-kon.edu.tr
Acta Cardiologica
|May 13, 2008
Summary
Smoking mentholated cigarettes has similar acute detrimental effects on coronary microvascular functions as regular cigarettes. Both types of smoking significantly impair coronary flow reserve (CFR).
Area of Science:
- Cardiology
- Cardiovascular Physiology
- Tobacco Research
Background:
- Mentholated cigarettes alter nicotine metabolism and increase toxin exposure.
- The impact of mentholated cigarette smoking on coronary microvascular function remains unclear.
- This study investigates potential differences in coronary flow reserve (CFR) impairment between mentholated and regular cigarette smoking.
Purpose of the Study:
- To determine if smoking mentholated cigarettes causes greater impairment of coronary flow reserve (CFR) compared to regular cigarettes.
- To assess the acute effects of mentholated and regular cigarette smoking on coronary microvascular function.
Main Methods:
- A study involving 20 healthy regular cigarette smokers and 22 non-smoking controls.
- Echocardiographic assessment of coronary flow reserve (CFR) at baseline.
- CFR measurement after subjects smoked two mentholated and two regular cigarettes.
Main Results:
- Smoking both mentholated and regular cigarettes led to a significant decline in CFR.
- CFR values decreased from 2.56 to 2.06 after mentholated cigarettes (P < 0.004).
- CFR values decreased from 2.56 to 2.14 after regular cigarettes (P < 0.005).
Conclusions:
- Smoking mentholated cigarettes acutely impairs coronary microvascular function to a similar extent as regular cigarettes.
- No significant difference was observed in the degree of CFR impairment between mentholated and regular cigarette smoking (P = 0.547).
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