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Published on: December 6, 2016
Obesity and risk of sleep related upper airway obstruction in Caucasian children
Mark Kohler1, Kurt Lushington, Richard Couper
1Centre for Sleep Research, The University of South Australia, Level 7, Playford Building, City East Campus, Frome Road, Adelaide, South Australia, Australia 5000. mark.kohler@unisa.edu.au
Insights
Childhood obesity is a weak predictor of upper airway obstruction in Australian Caucasian children. Age did not significantly influence obstruction, highlighting obesity
Area of Science:
- Pediatric Sleep Medicine
- Respiratory Physiology
- Childhood Obesity Research
Background:
- Obesity is a known risk factor for pediatric upper airway obstruction.
- The roles of age and ethnicity in this relationship require further investigation.
- Childhood obesity prevalence is increasing, necessitating a clearer understanding of its impact.
Purpose of the Study:
- To investigate the interplay between obesity, age, and upper airway obstruction.
- To quantify the contribution of obesity to sleep-disordered breathing in children.
- To examine these factors in Australian Caucasian children evaluated for snoring.
Main Methods:
- Retrospective case study of 190 children (4-12 years) undergoing polysomnography.
- Classification into Infrequent Snorers, Habitual Snorers, and Obstructive Sleep Apnea Syndrome (OSAS) groups.
- Analysis of body mass index (BMI) and age as predictors of obstructive apnea hypopnea index (OAHI).
Main Results:
- 35% of children were overweight or obese.
- Body mass index (BMI) was a significant but weak predictor of OAHI.
- Age was not a significant predictor of OAHI.
Conclusions:
- Obesity, not age, significantly predicted upper airway obstruction in the studied pediatric cohort.
- The predictive relationship between obesity and obstruction was weak.
- Findings are specific to Australian Caucasian children aged 4-12 years referred for snoring evaluation.
Background:
Obesity is thought to be a significant risk factor for upper airway obstruction during sleep in children. However, the moderating influences of age and ethnicity have not been well explored and the relative contribution of obesity per se to upper airway obstruction has yet to be quantified. Given the markedly increasing prevalence of childhood obesity, an objective understanding of the impact of obesity on upper airway obstruction is important. The purpose of the present study was to examine the interaction between obesity, age and upper airway obstruction in Australian Caucasian children referred for evaluation of snoring.
Methods:
This was a retrospective case study involving 190 children (4-12 y) who were referred for evaluation of upper airway obstruction and underwent one night of polysomnography at the Adelaide Women's and Children's Hospital Sleep Disorders Unit. Children were classified as Infrequent Snorers (n = 80), Habitual Snorers (n = 68) or Obstructive Sleep Apnea Syndrome (OSAS) (n = 42) (i.e., obstructive apnea hypopnea index (OAHI) > or = 1).
Results:
Thirty-five percent (66/190) of children were overweight or obese. Body mass index but not age was a significant but weak predictor of OAHI (< 5% of the variance).
Conclusion:
In Australian Caucasian children aged 4-12 years who snore, obesity but not age was a significant, albeit weak, predictor of upper airway obstruction during sleep.
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