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Updated: Jul 5, 2026

Voltage-Dependent Potassium Current Recording on H9c2 Cardiomyocytes via the Whole-Cell Patch-Clamp Technique
Published on: November 11, 2022
[Life threatening drug-induced hyperkaliemia--case report]
Joanna Konopa1, Barbara Bullo, Bolesław Rutkowski
1Klinika Nefrologii, Transplantologii i Chorób Wewnetrznych Akademii Medycznej w Gdańsku. jkonopa@amg.gda.pl
Abstract:
Patients with congestive heart failure are at increased risk of hyperkalemia due to coexisting morbidities and usage of multiple medications that impair potassium excretion--such as angiotensin-converting enzyme inhibitors or spironolactone. Because of the risk of this disturbance, knowledge of causation and prevention is mandatory. We described 3 patients with life threatening hyperkalemia (>8.5 mEq/t) caused by drugs. We showed the symptoms of increased potassium level, the list of medications and comorbidities predisposing to hyperkalemia. After a few days of medical treatment and dialysis, potasium level normalized in all of our patients.
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