Response of Sinorhizobium meliloti to elevated concentrations of cadmium and zinc
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Updated: Jul 5, 2026

An Anaerobic Biosensor Assay for the Detection of Mercury and Cadmium
Published on: December 17, 2018
Silvia Rossbach1, Danielle J Mai, Eric L Carter
1Department of Biological Sciences, Western Michigan University, Kalamazoo, MI 49008-5410, USA. Silvia.Rossbach@wmich.edu
Abstract:
Whole-genome transcriptional profiling was used to identify genes in Sinorhizobium meliloti 1021 that are differentially expressed during exposure to elevated concentrations of cadmium and zinc. Mutant strains with insertions in metal-regulated genes and in genes encoding putative metal efflux pumps were analyzed for their metal sensitivities, revealing a crucial role for the SMc04128-encoded P-type ATPase in the defense of S. meliloti against cadmium and zinc stress.
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