Effect of breastfeeding and sociodemographic factors on visual outcome in childhood and adolescence

Alicja R Rudnicka1, Christopher G Owen, Marcus Richards

  • 1Division of Community Health Sciences, St George's, University of London, London, United Kingdom. arudnick@sgul.ac.uk

Insights

Infant feeding does not influence childhood vision. Parental education, maternal age, birth weight, and birth order are linked to myopia development, indicating other environmental factors are key.

Area of Science:

  • Ophthalmology
  • Pediatrics
  • Public Health

Background:

  • Childhood myopia is a growing concern.
  • Early life factors like breastfeeding and birth weight are hypothesized to influence myopia development.
  • Understanding these early influences is crucial for prevention strategies.

Purpose of the Study:

  • To investigate the relationship between various early life factors and the development of reduced unaided vision (myopia) in childhood and adolescence.
  • To analyze the impact of infant feeding, parental education, maternal age, birth weight, sex, birth order, and socioeconomic status on visual acuity.

Main Methods:

  • Utilized data from three large British birth cohorts (1946, 1958, 1970) with over 42,000 participants.
  • Employed fixed-effects meta-analyses to pool adjusted odds ratios for reduced vision (6/12 or worse) at ages 10-11 and 15-16 years.
  • Controlled for multiple potential confounding factors in the analysis.

Main Results:

  • Breastfeeding rates declined across cohorts, but showed no association with vision outcomes.
  • Parental education, increased maternal age, higher birth order (more older siblings), and being female were associated with increased odds of reduced vision.
  • Higher birth weight was associated with decreased odds of reduced vision in childhood, but this association was null in adolescence.

Conclusions:

  • Infant feeding practices do not appear to significantly impact visual development or myopia.
  • Parental education, maternal age, sex, and birth order are consistently associated with reduced vision, highlighting the role of broader environmental influences.
  • Further research into these environmental factors is needed to understand and mitigate myopia progression in early life.
Abstract

Related Concept Videos

Photoreceptors and Visual Pathways01:22

Photoreceptors and Visual Pathways

At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category, whereas...
Development of Human Microbiota01:30

Development of Human Microbiota

The human microbiota begins developing at birth and undergoes continual change as we age. Infancy marks a critical period of microbial sensitivity, offering a “window of opportunity” during which beneficial microbes help mature the immune system. By age three, children typically develop a more stable and diverse microbial community. Newborns acquire microbes from their immediate environment; vaginal delivery favors maternal vaginal microbes, while cesarean births favor microbes from the skin...
Environmental Influences on Intelligence01:29

Environmental Influences on Intelligence

Despite the strong genetic influence on traits like intelligence, environmental factors significantly shape outcomes. For example, while over 90% of height variation is due to genetic differences, environmental factors such as nutrition also have a notable impact. Similarly, for intelligence, changes in a child's surroundings can significantly alter their IQ. Research shows that enriched environments boost children's academic success and help them develop key cognitive skills. Children from...
Diabetic Retinopathy01:27

Diabetic Retinopathy

DefinitionDiabetic retinopathy is a microvascular complication of diabetes affecting the retinal blood vessels.Risk FactorsDiabetic retinopathy is present in almost all individuals with type 1 diabetes and more than 60% of those with type 2 diabetes after two decades of disease.The risk increases with poor glycemic control, hypertension, dyslipidemia, smoking, pregnancy, and puberty.Although cataracts and glaucoma are also more frequent in people with diabetes, retinopathy remains the leading...