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Updated: Jul 5, 2026

Applying Cheminformatics to Develop a Structure Searchable Database of Analytical Methods
Published on: June 6, 2025
The ISS Dangerous Substances Classification and Labelling Database
Paola Di Prospero Fanghella1, Paolo Izzo, Eugenio Morassi
1Dipartimento di Ambiente e Connessa Prevenzione Primaria, Istituto Superiore di Sanità, Rome, Italy. paola.diprospero@iss.it
Abstract:
The database contains information about the substances marketed in the European Union at present. About 8000 out of 100 000 substances on the market are listed in Annex I (Directive 67/548/EC), the published list of substances with a harmonized classification and labelling. For each entry the database gives the following details: name, CAS number, EC number, classification, labelling,specific concentration limits, reference to the last amended EU and national law. There is also a section where the legislative frame is reported together with the EU Directives and the corresponding national implementation decrees. In addition to searching a substance by name/part of the name or identifying numbers the query can be done by symbols, R and S phrases, substance categories.
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