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Drug Classes and Categories

Drug Classes and Categories

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Applying Cheminformatics to Develop a Structure Searchable Database of Analytical Methods

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The ISS Dangerous Substances Classification and Labelling Database.

Paola Di Prospero Fanghella¹, Paolo Izzo, Eugenio Morassi

¹Dipartimento di Ambiente e Connessa Prevenzione Primaria, Istituto Superiore di Sanità, Rome, Italy. paola.diprospero@iss.it

Annali Dell'Istituto Superiore Di Sanita

|May 13, 2008

Summary

This database provides crucial information on substances marketed in the European Union, detailing their classification, labelling, and legal status. It serves as a vital resource for chemical safety and regulatory compliance.

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Published on: May 10, 2016

Area of Science:

Chemical safety and regulatory compliance
European Union chemical legislation
Substance identification and classification

Background:

The European Union (EU) currently has approximately 100,000 substances on the market.
Only about 8,000 substances are listed in Annex I of Directive 67/548/EC, featuring harmonized classification and labelling.
A comprehensive database is needed to consolidate information on these marketed substances.

Purpose of the Study:

To create a centralized database for substances marketed in the European Union.
To provide detailed information on chemical classification, labelling, and legal status.
To facilitate efficient substance searching and information retrieval.

Main Methods:

Compilation of data on approximately 8,000 substances listed in Annex I (Directive 67/548/EC).
Inclusion of key identifiers: name, CAS number, EC number.
Recording of classification, labelling, specific concentration limits, and relevant EU/national legislation.

Main Results:

The database contains detailed entries for substances with harmonized classification and labelling.
Each entry includes chemical identifiers, hazard information, and legal references.
Search functionalities allow queries by name, identifiers, symbols, R/S phrases, and substance categories.

Conclusions:

The database offers a valuable resource for chemical management and regulatory adherence within the EU.
It enhances accessibility to critical data on chemical substances, supporting safety assessments.
The comprehensive search options improve the efficiency of regulatory and scientific research.