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Updated: Jul 5, 2026

Direct Restart of a Replication Fork Stalled by a Head-On RNA Polymerase
07:27

Direct Restart of a Replication Fork Stalled by a Head-On RNA Polymerase

Published on: April 29, 2010

Promoter-proximal Pol II: when stalling speeds things up

Sergei Nechaev1, Karen Adelman

  • 1Laboratory of Molecular Carcinogenesis, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina 27709, USA. nechaevs@niehs.nih.gov

Cell Cycle (Georgetown, Tex.)
|May 13, 2008
PubMed
Summary

Gene expression regulation is not just about RNA polymerase II (Pol II) recruitment. Promoter-proximal Pol II stalling during early elongation is a key regulatory step for many genes, especially those involved in development and stimuli response.

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