Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Chronic Obstructive Pulmonary Disease I: Introduction01:23

Chronic Obstructive Pulmonary Disease I: Introduction

Chronic obstructive pulmonary disease is a common, preventable, and treatable respiratory disorder characterized by persistent symptoms and progressive airflow limitation. This limitation results from a combination of small-airway disease (obstructive bronchiolitis) and parenchymal destruction (emphysema), both driven by chronic inflammation from exposure to harmful particles or gases.The disease includes two main pathological entities: emphysema, marked by destruction of alveolar walls and...
Chronic Obstructive Pulmonary Disease-I: Introduction01:20

Chronic Obstructive Pulmonary Disease-I: Introduction

Chronic Obstructive Pulmonary Disease (COPD) is a long-lasting respiratory condition requiring continuous attention and care. It is a progressive lung disease that leads to breathing challenges due to airflow obstruction. It manifests as persistent respiratory symptoms and restricted airflow resulting from abnormalities in the airways and alveoli, usually due to long-term exposure to harmful particles or gases. COPD mainly consists of two primary conditions: emphysema and chronic bronchitis.
Chronic Obstructive Pulmonary Disease01:24

Chronic Obstructive Pulmonary Disease

COPD is defined as a heterogeneous lung condition marked by persistent respiratory symptoms such as dyspnea, cough, and sputum production, caused by abnormalities in the airways that cause airflow obstruction.
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...
Chronic Obstructive Pulmonary Disease-II: Pathophysiology01:20

Chronic Obstructive Pulmonary Disease-II: Pathophysiology

Chronic Obstructive Pulmonary Disease (COPD) pathophysiology is intricate and multifaceted, involving a complex interplay of physiological processes. Understanding these mechanisms is crucial for effectively managing and treating COPD. Here is an in-depth look at the critical elements in the pathophysiology of COPD:
Chronic Inflammation
COPD: Management Using Bronchodilators and Corticosteroids01:26

COPD: Management Using Bronchodilators and Corticosteroids

Chronic obstructive pulmonary isease (COPD) involves a group of progressive lung disorders characterized by persistent airflow limitation and chronic respiratory symptoms. Asthma-COPD Overlap Syndrome (ACOS), encompassing features of both asthma and Chronic obstructive pulmonary disease (COPD), is a group of progressive lung disorders that includes chronic bronchitis, emphysema, and refractory (non-reversible) asthma. ACOS leads to complex clinical presentations that combine the inflammatory...
Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies01:27

Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies

Assessing and diagnosing Chronic Obstructive Pulmonary Disease (COPD) involves a detailed approach that includes a comprehensive review of medical history, physical examination, and a variety of diagnostic tests. This thorough evaluation is essential to ensure an accurate diagnosis and guide effective management strategies.
Medical History

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Asthma Burden in Mild Adult Asthma in the PEARL Survey: Asthma Control and Health Status.

The journal of allergy and clinical immunology. In practice·2026
Same author

Drivers of disparities in asthma exacerbation and healthcare utilization: a quantitative analysis of neighborhood deprivation in Southern California, United States.

Preventive medicine reports·2026
Same author

A cohort study of forced vital capacity, airway obstruction, and survival in the multinational Burden of Obstructive Lung Disease study.

International journal of epidemiology·2026
Same author

An algorithm for the surveillance of occupational chronic obstructive pulmonary disease in Washington state.

Annals of the American Thoracic Society·2026
Same author

Willingness to provide naloxone: Survey of the National Dental Practice-Based Research Network.

Journal of opioid management·2026
Same author

Contralateral breast cancer after radiotherapy and hormone therapy in two cohorts of US breast cancer survivors.

British journal of cancer·2025

Related Experiment Video

Updated: Jul 5, 2026

Generation of a Chronic Obstructive Pulmonary Disease Model in Mice by Repeated Ozone Exposure
08:17

Generation of a Chronic Obstructive Pulmonary Disease Model in Mice by Repeated Ozone Exposure

Published on: August 25, 2017

COPD and occupational exposures: a case-control study.

Sheila Weinmann1, William M Vollmer, Victor Breen

  • 1Center for Health Research, Kaiser Permanente Northwest, Portland, Oregon 97227, USA. sheila.weinmann@kpchr.org

Journal of Occupational and Environmental Medicine
|May 13, 2008
PubMed
Summary

Occupational exposures to diesel exhaust, irritant gases, and dusts are linked to chronic obstructive pulmonary disease (COPD). These findings highlight workplace hazards contributing to COPD development, even in never-smokers.

More Related Videos

Alternative Therapy for Acute Exacerbation of Chronic Obstructive Pulmonary Disease: Moving Cupping Along Meridians
04:03

Alternative Therapy for Acute Exacerbation of Chronic Obstructive Pulmonary Disease: Moving Cupping Along Meridians

Published on: September 27, 2024

Related Experiment Videos

Last Updated: Jul 5, 2026

Generation of a Chronic Obstructive Pulmonary Disease Model in Mice by Repeated Ozone Exposure
08:17

Generation of a Chronic Obstructive Pulmonary Disease Model in Mice by Repeated Ozone Exposure

Published on: August 25, 2017

Alternative Therapy for Acute Exacerbation of Chronic Obstructive Pulmonary Disease: Moving Cupping Along Meridians
04:03

Alternative Therapy for Acute Exacerbation of Chronic Obstructive Pulmonary Disease: Moving Cupping Along Meridians

Published on: September 27, 2024

Area of Science:

  • Environmental Health
  • Occupational Medicine
  • Pulmonology

Background:

  • Occupational exposures are recognized as a significant cause of chronic obstructive pulmonary disease (COPD).
  • Understanding specific workplace hazards is crucial for preventing COPD.
  • Lifetime occupational history is a key factor in assessing COPD risk.

Purpose of the Study:

  • To evaluate the association between various occupational exposures and the prevalence of chronic obstructive pulmonary disease (COPD).
  • To identify specific occupational hazard categories linked to COPD development.
  • To examine these associations in a population-based case-control study.

Main Methods:

  • A case-control study comparing 388 COPD cases (≥45 years) with 356 controls, matched for age, sex, and smoking history.
  • Logistic regression was used to compute odds ratios for eight occupational hazard categories and three composite exposure measures.
  • Lifetime occupational histories were analyzed to assess cumulative exposures.

Main Results:

  • Strong associations were found between COPD and occupational exposures to diesel exhaust, irritant gases and vapors, mineral dust, and metal dust.
  • Aggregate exposures to gases, vapors, solvents, or sensitizers (GVSS) and combined dust, GVSS, or diesel exhaust also showed significant links to COPD.
  • Similar exposure-associated patterns were observed in a subgroup of never-smokers.

Conclusions:

  • This population-based study reinforces the causal link between occupational exposures and chronic obstructive pulmonary disease (COPD).
  • Specific workplace exposures, including dusts and gases, are identified as significant risk factors for COPD.
  • Findings are relevant for prevention strategies targeting occupational lung diseases.