Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Cells of the Epidermis

Cells of the Epidermis

The epidermis is made of four or five layers of epithelial cells, depending on its location in the body. From deep to superficial, these layers are the stratum basale, stratum spinosum, stratum granulosum, stratum lucidum, and stratum corneum.
The cells in all these layers except the stratum basale are called keratinocytes, a type of cell that manufactures and stores the protein keratin. The keratinocytes in the stratum corneum are dead and regularly slough away, being replaced by cells from...

Renewal of Skin Epidermal Stem Cells

Renewal of Skin Epidermal Stem Cells

The skin is divided into epidermis, dermis, and hypodermis, the skin's outermost, middle, and inner layers. The human epidermal layer regularly undergoes renewal, where old, dead cells are replaced by new cells. Epidermal stem cells or EpiSCs divide and differentiate to restore the lost cells. For the renewal process, some EpiSCs continuously self-renew. In contrast, few others differentiate into transit-amplifying cells, which later form prickle or spinous cells, followed by granular cells,...

Papillary Dermis

Papillary Dermis

Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
Papillary Layer
The papillary layer is made of loose, areolar connective tissue, which means the collagen and...

Layers of the Epidermis

Layers of the Epidermis

The epidermis, the outermost layer of the skin, is composed of several distinct layers. From deep to superficial, the layers of the epidermis are as follows:
Stratum Basale
Stratum basale, also known as the stratum germinativum, is the deepest layer of the epidermis. It is composed of a single layer of actively dividing cells called basal cells or basal keratinocytes. These cells constantly undergo cell division to replenish the upper layers of the epidermis. Additionally, melanocytes, which...

Hand hygiene

Hand hygiene

Asepsis is the practice of preventing or breaking the chain of infection. The nurse employs aseptic techniques to prevent the spread of microorganisms and reduce the risk of diseases. Hand hygiene is the cornerstone of aseptic techniques and is classified into medical and surgical asepsis. Medical asepsis includes hand hygiene and the use of gloves. Surgical asepsis, or the sterile technique, refers to practices that render and keep objects and areas free of microorganisms.
Hand washing...

Acne Infection

Acne Infection

Acne is a multifactorial skin condition primarily affecting adolescents and young adults, with a global prevalence estimated to exceed 75% in this demographic. The condition is characterized by the formation of comedones (blackheads and whiteheads), papules, pustules, nodules, and, in severe cases, cysts, particularly in areas rich in sebaceous glands such as the face, neck, chest, and back. The pathogenesis involves increased sebum production, follicular hyperkeratinization, colonization by...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Dermatopathology.

Clinical and experimental dermatology·2026

Same author

The role of surgical skin grafting in pyoderma gangrenosum.

Dermatology online journal·2026

Same author

A Widespread Pruritic Blistering Eruption in a Young Female.

International journal of dermatology·2026

Same author

Postpartum pruritic urticarial papules and plaques of pregnancy with an atypical distribution and late onset.

BMJ case reports·2025

Same author

Tender nodules over bilateral forearms in a patient with stable ulcerative colitis.

Clinical and experimental dermatology·2025

Same author

Tender nodules on the sole of the foot.

Clinical and experimental dermatology·2024

Search research articles

Related Experiment Video

Updated: Jul 5, 2026

Enhancement of Facial Rejuvenation Through a Combination of 1565 nm Non-Ablative Fractional Laser with 30% Supramolecular Salicylic Acid

Enhancement of Facial Rejuvenation Through a Combination of 1565 nm Non-Ablative Fractional Laser with 30% Supramolecular Salicylic Acid

Published on: September 27, 2024

Superficial and medium-depth chemical peels.

Eileen Clark¹, Lawrence Scerri

¹Department of Dermatology, University of Malta, Sir Paul Boffa Hospital, Floriana, Malta.

Clinics in Dermatology

|May 13, 2008

Summary

Chemical peels offer facial rejuvenation by resurfacing skin layers. Understanding skin anatomy and proper care are key for treating photoaging, dyschromias, and acne scars effectively.

Area of Science:

Dermatology
Aesthetic Medicine

Background:

Chemicals have been used for facial rejuvenation historically.
Understanding skin anatomy and wound healing is crucial for chemical peeling.
Chemical peels are categorized by the depth of skin resurfacing achieved.

Purpose of the Study:

To explain the principles of chemical peeling for facial rejuvenation.
To outline the classification and indications of chemical peels.
To emphasize the importance of patient selection and post-peel care.

Main Methods:

Classification of chemical peels based on skin resurfacing depth.
Identification of main clinical indications: photoaging, dyschromias, and acne scars.
Correlation of clinical changes with histologic depth.

More Related Videos

Roller Microneedle Combined with Tranexamic Acid Solution in Treating Melasma

Roller Microneedle Combined with Tranexamic Acid Solution in Treating Melasma

Published on: January 19, 2024

Using a 1064-nm Picosecond Neodymium-Doped Yttrium Aluminum Garnet Laser for Periorbital Hyperpigmentation

Using a 1064-nm Picosecond Neodymium-Doped Yttrium Aluminum Garnet Laser for Periorbital Hyperpigmentation

Published on: May 23, 2025

Related Experiment Videos

Last Updated: Jul 5, 2026

Enhancement of Facial Rejuvenation Through a Combination of 1565 nm Non-Ablative Fractional Laser with 30% Supramolecular Salicylic Acid

Enhancement of Facial Rejuvenation Through a Combination of 1565 nm Non-Ablative Fractional Laser with 30% Supramolecular Salicylic Acid

Published on: September 27, 2024

Roller Microneedle Combined with Tranexamic Acid Solution in Treating Melasma

Roller Microneedle Combined with Tranexamic Acid Solution in Treating Melasma

Published on: January 19, 2024

Using a 1064-nm Picosecond Neodymium-Doped Yttrium Aluminum Garnet Laser for Periorbital Hyperpigmentation

Using a 1064-nm Picosecond Neodymium-Doped Yttrium Aluminum Garnet Laser for Periorbital Hyperpigmentation

Published on: May 23, 2025

Main Results:

Chemical peels are effective for cosmetic concerns like photoaging, dyschromias, and acne scars.
Patient selection, skin preparation, and post-peel management are critical for successful outcomes.
Combining chemical peels with other treatments enhances results for photoaging.

Conclusions:

Chemical peeling is a well-established method for facial rejuvenation.
Adherence to proper protocols ensures patient safety and treatment efficacy.
Further research may explore synergistic effects with other aesthetic procedures.