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Updated: Jul 5, 2026

A Murine Model of Irreversible and Reversible Unilateral Ureteric Obstruction
Published on: December 20, 2014
[Ureter drugs]
1Service d'urologie et transplantation, CHU d'Amiens, hôpital Sud, boulevard Laennec, 80054 Salouel cedex, France. gauthier.raynal@etud.u-picardie.fr
Abstract:
Many improvements have been made recently in the field of the ureteral smooth muscle pharmacology. After a brief summary on physiological basis, we review what is known about effects on ureter of different drugs class. In a second part, we review clinical applications for renal colic analgesia, calculi expulsive medical therapy, ESWL adjuvant treatment and preoperative treatment before retrograde access. There are now sufficient data on NSAID and alpha-blockers. beta-agonists, especially for beta3 selective ones, and topical drugs before retrograde access are interesting and should be further evaluated.
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