Related Experiment Video
Updated: Jul 5, 2026
Establishment of a Murine Pulp Exposure Model with a Novel Mouth-Gag for Pulpitis Research
Published on: October 27, 2023
The permeability of artificial dentine carious lesions
T O Elgalaid1, S L Creanor, S Creanor
1Newcastle upon Tyne Dental Hospital, Richardson Road, Newcastle upon Tyne NE2 4AZ, UK. taher33@hotmail.com
Objective:
This study aimed to verify whether two demineralisation solutions, with different fluoride concentrations, would produce subsurface lesions in dentine, as assessed by microradiography, with different mineral loss profiles and, subsequently, to determine the dentine permeability of the two altered tissues.
Methods:
Forty-five human coronal portions were prepared and randomly divided into two test groups (20 specimens each) with the remaining five as a control group. Each test group was exposed to a demineralisation solution containing either 1 or 5 ppm fluoride for five days.
Results:
There were highly significant differences between the two test groups for all microradiographic parameters, except for lesion depth. The increase in dentine permeability from baseline to day 5 was statistically significant within each of the two test groups, but not for the control group.
Conclusion:
The differences in the mineral content profile of the two lesions did not influence the magnitude of change in their permeability.
Related Concept Videos
01:21Tooth Anatomy
The Crown, Neck, and Root
The visible part of the tooth is referred to as the crown. It's covered by enamel, the hardest substance in the human body. The crown is uniquely shaped for each type of tooth, allowing for different functions such as cutting, tearing, or grinding food.
01:25Permeability of Concrete