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Related Concept Videos

Local Anesthetics: Adverse Effects01:12

Local Anesthetics: Adverse Effects

While local anesthetics are generally safe and well-tolerated, they can occasionally cause adverse effects that vary in severity. Local anesthetics can induce toxicity at two distinct levels. They can either produce local effects through direct contact with the neural elements or be absorbed into the bloodstream from the injection site, leading to systemic effects.
Once absorbed into the systemic circulation, local anesthetics can affect the organs that depend on the functioning of sodium...
Acute Pyelonephritis I: Introduction01:27

Acute Pyelonephritis I: Introduction

Pyelonephritis is a bacterial infection that primarily affects the renal parenchyma and collecting system, including the renal pelvis, tubules, and interstitial tissue of one or both kidneys. It can be classified as either acute—a sudden, severe infection—or chronic, which refers to long-term or recurrent kidney infections.The primary cause of acute pyelonephritis (APN) is bacterial infection, with Escherichia coli accounting for approximately 70-80% of cases. Other bacteria, such as Proteus,...
Diphtheria01:28

Diphtheria

Diphtheria is an acute, toxin-mediated infectious disease that primarily affects the upper respiratory tract. It is caused by Corynebacterium diphtheriae, a Gram-positive, pleomorphic rod that lacks spore-forming capability and exhibits a characteristic club-shaped morphology under microscopic examination. While C. diphtheriae can asymptomatically colonize mucosal surfaces, clinical disease manifests only when the bacterial strain is lysogenized by a specific β-corynephage. This phage...
Acute Pyelonephritis II: Diagnostic Studies and Management01:28

Acute Pyelonephritis II: Diagnostic Studies and Management

Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...
Acute Pharyngitis01:30

Acute Pharyngitis

Introduction
Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
Classification
Acute pharyngitis can be categorized based on its underlying cause:
Acute Pancreatitis I: Introduction01:25

Acute Pancreatitis I: Introduction

Acute pancreatitis is the sudden inflammation of the pancreas caused by the early activation of digestive enzymes, leading to the autodigestion of pancreatic tissue. This results in local inflammation and, in severe cases, systemic complications.EtiologyUnderstanding the underlying causes is crucial, as identifying the etiology guides treatment and anticipates complications. Acute pancreatitis can be triggered by various factors, typically grouped into the following clinical categories.Biliary...

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Related Experiment Videos

Enalaprilat induced acute parotitis.

V Chauhan1, R C Negi, A Sharma

  • 1Department of Medicine, Indira Gandhi Medical College, Shimla.

The Journal of the Association of Physicians of India
|May 14, 2008
PubMed
Summary

Acute bilateral parotitis is a rare drug complication. This case report details a patient experiencing this reaction after intravenous enalaprilat, resolving with prompt treatment.

Related Experiment Videos

Area of Science:

  • Pharmacology
  • Otolaryngology
  • Adverse Drug Reactions

Background:

  • Drug-induced acute parotitis is an infrequent adverse event, with limited documented cases associated with specific medications.
  • Acute bilateral parotitis has not been previously reported in association with intravenous enalaprilat administration.

Observation:

  • A female patient presented with acute bilateral parotitis.
  • The parotitis developed rapidly, occurring within minutes following the administration of intravenous enalaprilat.

Findings:

  • This case represents the first documented instance of acute bilateral parotitis linked to intravenous enalaprilat.
  • The patient's symptoms resolved within 24 hours after discontinuing enalaprilat and initiating symptomatic management.

Implications:

  • This report highlights the potential for intravenous enalaprilat to induce acute bilateral parotitis.
  • Clinicians should consider enalaprilat as a potential cause of acute parotitis in patients presenting with these symptoms.
  • Early recognition and drug cessation are crucial for managing this rare adverse reaction.