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Anogenital Distance and Perineal Measurements of the Pelvic Organ Prolapse (POP) Quantification System
Published on: September 20, 2018
Does pelvic organ prolapse reduction affect abdominal leak point pressures?
James L Whiteside1, Alexei Viazmenski, Kris Strohbehn
1Department of Obstetrics and Gynecology, Dartmouth Medical School, Hanover, New Hampshire 03756, USA. james.l.whiteside@hitchcock.org
The Journal of Reproductive Medicine
|May 14, 2008
Summary
Reducing pelvic organ prolapse (POP) significantly decreases cystometric leak point pressure (LPP). This finding suggests prolapse reduction may improve stress urinary incontinence by lowering LPP.
Area of Science:
- Urology
- Gynecology
- Female Pelvic Medicine
Background:
- Pelvic organ prolapse (POP) can be associated with stress urinary incontinence (SUI).
- Leak point pressure (LPP) is a urodynamic measure of SUI severity.
- The effect of POP reduction on LPP requires further investigation.
Purpose of the Study:
- To investigate the relationship between pelvic organ prolapse reduction and cystometric leak point pressure.
- To determine if reducing POP decreases LPP in women with SUI.
Main Methods:
- Retrospective review of 44 women with POP and SUI undergoing multichannel urodynamic investigation.
- Comparison of LPP with and without vaginal support (prolapse reduction).
- Statistical analysis of the mean difference in LPP.
Main Results:
- Pelvic organ prolapse reduction was associated with a mean decrease in LPP of 16.1 cm H2O (p=0.0005).
- 15% of subjects leaked only with prolapse, and 4% leaked only without prolapse reduction.
- Significant decrease in LPP observed in women with POP and SUI upon prolapse reduction.
Conclusions:
- Reduction of pelvic organ prolapse is linked to a significant decrease in cystometric leak point pressure.
- This suggests that POP reduction may be a viable strategy for managing SUI.

