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Isolation, Transfection, and Culture of Primary Human Monocytes
Published on: December 16, 2019
CMV oophoritis in an AIDS patient
1Department of Pathology The University of Rochester School of Medicine and Dentistry Rochester NY USA.
Infectious Diseases in Obstetrics and Gynecology
|January 1, 1995
Summary
This case study describes the first instance of symptomatic cytomegalovirus (CMV) pelvic infection in a woman with acquired immunodeficiency syndrome (AIDS). The findings highlight the need for awareness of opportunistic CMV infections in women with AIDS.
Area of Science:
- Gynecologic pathology
- Infectious diseases
- Virology
Background:
- Disseminated cytomegalovirus (CMV) infection typically affects immunocompromised individuals and neonates.
- Acquired immunodeficiency syndrome (AIDS) patients commonly present with CMV lung and eye involvement.
- Symptomatic CMV pelvic infections have not been previously reported in women.
Purpose of the Study:
- To report the first case of acute symptomatic CMV infection of the female genital tract in a woman with AIDS.
- To document CMV involvement in the ovaries, endometrium, and endosalpinx.
Main Methods:
- Case report detailing a patient with AIDS presenting with symptoms of CMV oophoritis.
- Histopathological examination to identify CMV in reproductive organs.
Main Results:
- The patient's symptoms were attributed to acute CMV oophoritis.
- CMV was detected in the endometrium and endosalpinx, previously unreported sites.
Conclusions:
- The rising incidence of AIDS in women necessitates increased clinical awareness.
- Opportunistic, symptomatic CMV pelvic infections should be considered in women with AIDS.
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