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Related Concept Videos

Cryptococcal Meningitis01:27

Cryptococcal Meningitis

Cryptococcal meningitis is a life-threatening opportunistic infection predominantly associated with HIV/AIDS, accounting for over 100,000 deaths annually worldwide. However, it also affects individuals with other forms of immunosuppression, including those undergoing immunosuppressive therapy, organ transplant recipients, patients with innate immunodeficiencies, and individuals with hematological disorders. The infection is caused mainly by Cryptococcus neoformans and Cryptococcus gattii,...
Secondary Lymphoid Organs01:15

Secondary Lymphoid Organs

Secondary organs, including lymph nodes, the spleen, and mucosa-associated lymphoid tissue (MALT), work harmoniously to protect us from disease and infection.
The spleen is a vital organ in the lymphatic system, nestled in the upper left side of the abdomen. It is composed of two primary regions: the red pulp and the white pulp, each having distinct functions. The red pulp performs a significant role in blood filtration. It efficiently purges the blood of old or damaged red blood cells and...

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Related Experiment Video

Updated: Jul 5, 2026

Saline Lavage for Sampling of the Canine Nasal Immune Microenvironment
04:35

Saline Lavage for Sampling of the Canine Nasal Immune Microenvironment

Published on: December 27, 2024

[Cryptococcal lymphadenitis in a dog.].

B Acosta1, P Alvarez, S Deniz

  • 1Departamento de Patología Animal, Facultad de Veterinaria de Las Palmas de Gran Canaria, Spain. bacosta@cicei.ulpgc.es.

Revista Iberoamericana De Micologia
|May 14, 2008
PubMed
Summary
This summary is machine-generated.

Canine cryptococcosis caused by Cryptococcus neoformans presents with fever, vomiting, diarrhea, and swollen lymph nodes. This fungal infection can reoccur, affecting the nervous system and leading to euthanasia.

Related Experiment Videos

Last Updated: Jul 5, 2026

Saline Lavage for Sampling of the Canine Nasal Immune Microenvironment
04:35

Saline Lavage for Sampling of the Canine Nasal Immune Microenvironment

Published on: December 27, 2024

Area of Science:

  • Veterinary Mycology
  • Canine Infectious Diseases

Context:

  • Cryptococcosis is a systemic fungal infection caused by encapsulated yeasts.
  • Canine cryptococcosis can manifest with diverse clinical signs, including lymphadenitis and gastrointestinal issues.

Purpose:

  • To report a unique case of recurrent canine cryptococcosis.
  • To highlight the diagnostic challenges and clinical progression of the disease in a dog.

Summary:

  • A dog presented with fever, vomiting, diarrhea, and bilateral lymphadenitis.
  • Biopsy confirmed Cryptococcus neoformans infection.
  • The dog relapsed 30 months later with neurological signs and cachexia, with C. neoformans detected in bone marrow, CNS, and lymph nodes post-mortem.

Impact:

  • This case underscores the potential for cryptococcosis recurrence in dogs.
  • It emphasizes the importance of considering fungal infections in dogs with persistent or relapsing symptoms.
  • Highlights the diagnostic utility of histopathology and microbiology in identifying Cryptococcus neoformans.