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Published on: November 27, 2014
[Five cases of zygomycosis.]
A Del Palacio1, M J Ramos, A Pérez
1Servicio de Microbiología, Hospital Universitario 12 de Octubre, Madrid, Spain. apalacioh.hdoc@salud.madrid.org.
Revista Iberoamericana De Micologia
|May 14, 2008
Summary
This study details cutaneous zygomycosis cases, identifying Absidia, Rhizopus, and Mucor species. Combined antifungal and surgical treatments proved effective for most patients with zygomycosis.
Area of Science:
- Mycology
- Dermatology
- Infectious Diseases
Context:
- Cutaneous zygomycosis is a rare but serious fungal infection.
- Predisposing factors include immunosuppression, diabetes, and corticosteroid use.
- Early diagnosis and treatment are crucial for patient outcomes.
Purpose:
- To report on the diagnosis, treatment, and outcomes of cutaneous zygomycosis.
- To identify the causative agents and predisposing factors.
- To evaluate the efficacy of combined antifungal and surgical interventions.
Summary:
- Four patients with cutaneous zygomycosis were diagnosed using histological and mycological methods.
- Infections were caused by Absidia corymbifera, Rhizopus stolonifer, and Mucor circinelloides.
- Combined treatment with amphotericin B (conventional and liposomal) and surgery resulted in favorable outcomes for three patients.
- One patient with suspected pulmonary zygomycosis had an unfavorable outcome.
Impact:
- Highlights the importance of prompt diagnosis and multimodal treatment for cutaneous zygomycosis.
- Provides insights into the clinical presentation and management of rare fungal infections.
- Emphasizes the role of predisposing factors in disease development and patient prognosis.
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