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Updated: Jul 5, 2026

A Magnetic Resonance Imaging-based Computational Protocol for Analysis of Plaque Morphology and Hemodynamics in Patients with Carotid Artery Stenosis
09:36

A Magnetic Resonance Imaging-based Computational Protocol for Analysis of Plaque Morphology and Hemodynamics in Patients with Carotid Artery Stenosis

Published on: August 12, 2025

Current management of extracranial carotid artery disease

Rabih A Chaer1, Brian DeRubertis, Sheela Patel

  • 1New York Presbyterian Hospital, Division of Vascular Surgery, Cornell University, Weill Medical College, NY, USA.

Reviews on Recent Clinical Trials
|May 14, 2008
PubMed

Insights

Carotid artery stenosis, a cause of ischemic stroke, is treated with surgery (CEA) or angioplasty with stenting (CAS). This review compares traditional CEA data with recent CAS results for extracranial carotid artery stenosis.

Area of Science:

  • Neurology
  • Vascular Surgery
  • Interventional Cardiology

Background:

  • Stroke is a leading cause of death, with ischemic strokes often linked to carotid artery disease.
  • Carotid endarterectomy (CEA) is a traditional surgical treatment for carotid stenosis.
  • Emerging endovascular techniques offer alternatives for specific patient groups.

Purpose of the Study:

  • To review current management strategies for extracranial carotid artery stenosis.
  • To compare the efficacy and safety of carotid angioplasty and stenting (CAS) with CEA.
  • To analyze recent outcomes of CAS in treating carotid stenosis.

Main Methods:

  • Review of existing data on carotid endarterectomy (CEA).
  • Critical analysis of recent results from carotid angioplasty and stenting (CAS) studies.
  • Comparison of outcomes between surgical and endovascular interventions for carotid stenosis.

Main Results:

  • CEA has proven efficacy in reducing stroke risk for severe symptomatic and asymptomatic carotid stenosis.
  • CAS is a viable alternative for high-surgical-risk patients and stenoses inaccessible to surgery.
  • Recent CAS data provides a critical comparison point to traditional CEA outcomes.

Conclusions:

  • Both CEA and CAS are established treatments for carotid stenosis, each with specific indications.
  • CAS offers a less invasive option, particularly for high-risk or surgically inaccessible cases.
  • Ongoing evaluation of CAS outcomes is crucial for optimizing stroke prevention strategies.

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