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Factors associated with suboptimal compliance to vaccinations in children in developed countries: a systematic review

Matthew E Falagas1, Effie Zarkadoulia

  • 1Alfa Institute of Biomedical Sciences (AIBS), Athens, Greece. m.falagas@aibs.gr

Current Medical Research and Opinion
|May 14, 2008
PubMed

Insights

Suboptimal vaccination compliance is a public health issue. Factors like socioeconomic status, parental education, and healthcare access significantly impact immunization rates in children and adolescents.

Area of Science:

  • Public Health
  • Pediatrics
  • Immunization

Background:

  • Suboptimal vaccination compliance remains a significant public health challenge.
  • Understanding factors influencing immunization uptake is crucial for improving population health outcomes.

Purpose of the Study:

  • To systematically review and evaluate factors associated with suboptimal vaccination compliance in children and adolescents in developed countries.
  • To identify key parental-childhood and healthcare-related determinants of vaccination adherence.

Main Methods:

  • A systematic review of the PubMed and Cochrane databases was conducted.
  • Studies were categorized based on their use of an analytical statistical approach.
  • 39 articles with original data were evaluated in detail from 553 potentially relevant articles.

Main Results:

  • Parental-childhood factors associated with suboptimal compliance include non-white race, low socioeconomic status, lack of insurance, lower parental education, and negative beliefs about vaccines.
  • Healthcare system factors include provider skepticism, inadequate support, limited accessibility, and transportation issues.
  • Specific barriers identified include fear of side effects, forgetting schedules, sick child delays, and delayed well-child visits.

Conclusions:

  • Recognizing these factors allows for targeted interventions to improve vaccination rates.
  • Strategies such as reminder systems, health education, and enhanced provider-parent communication are recommended.
  • Addressing socioeconomic and healthcare system barriers is vital for increasing immunization compliance.
Abstract

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