Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Mechanical Systems01:22

Mechanical Systems

Mechanical systems are analogous to to electrical networks where springs and masses play similar roles to inductors and capacitors, respectively. A viscous damper in mechanical systems functions similarly to a resistor in electrical networks, dissipating energy. The forces acting on a mass in such systems include an applied force in the direction of motion, counteracted by forces from the spring, a viscous damper, and the mass's acceleration. This interplay of forces is mathematically described...
Electro-mechanical Systems01:19

Electro-mechanical Systems

Electromechanical systems are intricate configurations that effectively combine electrical and mechanical elements to achieve a desired outcome. Central to many of these systems is the DC motor, a device that converts electrical energy into mechanical motion, enabling various applications ranging from simple fans to complex robotic mechanisms.
A key component of the DC motor is the armature, a rotating circuit positioned within a magnetic field. As an electric current passes through the...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Cooperativity, entropy, and effective concentration in DNA origami self-replication.

Science advances·2026
Same author

A tunable autonomous RNA-fueled micro-engine.

Nature communications·2026
Same author

Blunt-force assembly of programmable DNA architectures using π-π stacking.

Nature communications·2026
Same author

Cloning, Expression and Purification of the Beta Subunit of Cholera Toxin Using Escherichia coli as an Expression Host and pET-24a(+) as a Cloning Vector.

Cureus·2026
Same author

Dynamic Control of DNA Origami Self-Assembly by Transcriptional Modules.

Journal of the American Chemical Society·2026
Same author

DNA Glass: Encasing Diffraction-Quality, Mesoporous DNA Crystals in Architected Silica.

Angewandte Chemie (International ed. in English)·2025

Related Experiment Video

Updated: Jul 5, 2026

Design and Synthesis of a Reconfigurable DNA Accordion Rack
07:44

Design and Synthesis of a Reconfigurable DNA Accordion Rack

Published on: August 15, 2018

A DNA-based nanomechanical device with three robust states.

Banani Chakraborty1, Ruojie Sha, Nadrian C Seeman

  • 1Department of Chemistry, New York University, New York, NY 10003, USA.

Proceedings of the National Academy of Sciences of the United States of America
|May 14, 2008
PubMed
Summary

Researchers developed a novel DNA nanotechnology system. This system enables three distinct structural states from a single intermediate, paving the way for advanced molecular computing and logic systems.

More Related Videos

Folding and Characterization of a Bio-responsive Robot from DNA Origami
07:59

Folding and Characterization of a Bio-responsive Robot from DNA Origami

Published on: December 3, 2015

DNAzyme 10-23 - Based Nanomachines for Nucleic Acid Recognition
07:16

DNAzyme 10-23 - Based Nanomachines for Nucleic Acid Recognition

Published on: February 9, 2024

Related Experiment Videos

Last Updated: Jul 5, 2026

Design and Synthesis of a Reconfigurable DNA Accordion Rack
07:44

Design and Synthesis of a Reconfigurable DNA Accordion Rack

Published on: August 15, 2018

Folding and Characterization of a Bio-responsive Robot from DNA Origami
07:59

Folding and Characterization of a Bio-responsive Robot from DNA Origami

Published on: December 3, 2015

DNAzyme 10-23 - Based Nanomachines for Nucleic Acid Recognition
07:16

DNAzyme 10-23 - Based Nanomachines for Nucleic Acid Recognition

Published on: February 9, 2024

Area of Science:

  • Nanotechnology
  • Molecular Biology
  • Biophysics

Background:

  • DNA-based devices offer precise control through sequence-dependent interactions.
  • Existing DNA devices often have limited structural end states (one or two).
  • A need exists for more complex, multi-state DNA nanostructures for advanced applications.

Purpose of the Study:

  • To engineer a DNA device capable of achieving three distinct, structurally robust end states.
  • To demonstrate precise control over DNA nanostructures using specific DNA strands.
  • To explore the potential for trinary logic and complex molecular systems.

Main Methods:

  • Extension of the PX-JX(2) DNA device architecture.
  • Utilizing specific DNA 'set strands' to trigger transitions.
  • Characterization of structural changes using gel electrophoresis, fluorescence resonance energy transfer (FRET), and atomic force microscopy (AFM).

Main Results:

  • Successfully demonstrated a DNA system with three controllable, robust end states from a single floppy intermediate.
  • Identified three distinct motions governing state transitions: twofold rotation, translation (2.1-2.5 nm), and twofold screw rotation.
  • Validated state transitions through multiple experimental techniques.

Conclusions:

  • This DNA system provides a foundation for trinary logic operations.
  • The ability to achieve multiple states from a single intermediate significantly expands the complexity achievable in DNA nanotechnology.
  • Potential for developing systems with N devices capable of 3(N) structural states, enabling highly complex molecular computation.