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Characterizing Salmonella Typhimurium-induced Septic Peritonitis in Mice
Published on: July 29, 2022
Salmonella typhi and pregnancy: a case report
B Gluck1, K D Ramin, S M Ramin
1Department of Obstetrics and Gynecology University of Texas Southwestern Medical Center 5323 Harry Hines Boulevard, Dallas, TX 75235-9032, USA.
Infectious Diseases in Obstetrics and Gynecology
|January 1, 1994
Summary
Salmonella typhi infection during pregnancy can cause severe illness. Prompt diagnosis and antibiotic treatment are crucial for favorable outcomes in mothers and newborns.
Area of Science:
- Obstetrics and Gynecology
- Infectious Diseases
- Maternal-Fetal Medicine
Background:
- Salmonella typhi (S. typhi) infection poses significant risks for maternal and fetal health.
- Febrile illnesses in pregnancy, particularly with hemolysis, may indicate serious conditions like chorioamnionitis or pyelonephritis.
- S. typhi should be considered in pregnant patients presenting with fever and hemolysis.
Purpose of the Study:
- To present a case of Salmonella typhi infection complicating pregnancy.
- To highlight the importance of considering S. typhi in pregnant patients with fever and hemolysis.
Main Methods:
- A case report of a primigravida at 26 weeks gestation presenting with fever and severe hemolysis.
- Diagnostic workup included peripheral blood smear, bilirubin levels, and blood, stool, and urine cultures.
- Empirical antibiotic treatment was initiated and adjusted based on culture results.
Main Results:
- Blood cultures confirmed Salmonella typhi infection.
- The patient's fever resolved within 5 days of appropriate antibiotic therapy (gentamicin and ceftriaxone).
- A healthy infant was delivered vaginally at term.
Conclusions:
- Typhoid fever is a serious concern during pregnancy.
- Early consideration of S. typhi in pregnant patients with fever and hemolysis is vital.
- Prompt diagnosis and appropriate antibiotic therapy are essential for successful management.
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