Transition Metal Ion Complexes of Schiff-bases. Synthesis, Characterization and Antibacterial Properties
Z H Chohan1, A Munawar, C T Supuran
1Department of Chemistry Islamia University Bahawalpur Pakistan.
Abstract:
Some novel transition metal [Co(II), Cu(II), Ni(II) and Zn(II)] complexes of substituted pyridine Schiff-bases have been prepared and characterized by physical, spectral and analytical data. The synthesized Schiff-bases act as deprotonated tridentate for the complexation reaction with Co(II), Ni(II) and Zn(II) ions. The new compounds, possessing the general formula [M(L)(2)] where [M=Co(II), Cu(II), Ni(II) and Zn(II) and HL=HL(1), HL(2), HL(3) and HL(4)] show an octahedral geometry. In order to evaluate the effect of metal ions upon chelation, the Schiff bases and their complexes have been screened for antibacterial activity against the strains such as Escherichia coli,Staphylococcus aureus, and Pseudomonas aeruginosa. The complexed Schiff bases have shown to be more antibacterial against one more bacterial species as compared to uncomplexed Schiff-bases.
More Related Videos
Related Concept Videos
Metal-Ligand Bonds
In these complexes, transition metals form coordinate covalent bonds, a kind of Lewis acid-base interaction in which both of the electrons in the bond are contributed by a donor (Lewis base) to an electron acceptor (Lewis acid). The Lewis acid in...
Formation of Complex Ions
Complexation Equilibria: Factors Influencing Stability of Complexes
EDTA: Chemistry and Properties
Extraction: Advanced Methods
Complexation Equilibria: The Chelate Effect


