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Related Concept Videos

Metal-Ligand Bonds02:51

Metal-Ligand Bonds

The hemoglobin in the blood, the chlorophyll in green plants, vitamin B-12, and the catalyst used in the manufacture of polyethylene all contain coordination compounds. Ions of the metals, especially the transition metals, are likely to form complexes.
In these complexes, transition metals form coordinate covalent bonds, a kind of Lewis acid-base interaction in which both of the electrons in the bond are contributed by a donor (Lewis base) to an electron acceptor (Lewis acid). The Lewis acid in...
Complexation Equilibria: Factors Influencing Stability of Complexes01:09

Complexation Equilibria: Factors Influencing Stability of Complexes

In complexation reactions, metal cations are the electron pair acceptors, and the ligands are the electron pair donors. The stability of the metal complexes depends primarily on the complexing ability of the central metal ion and the nature of the ligands. Generally, the complexing ability of the metal ion depends on the size and charge of the ion. As the metal ion size increases, the stability of the metal complexes decreases, provided that the valency of the metal ion and the ligands remain...
Complexation Equilibria: The Chelate Effect01:19

Complexation Equilibria: The Chelate Effect

In complexation reactions, metal atoms or cations interact with ligands to form donor-acceptor adducts called metal complexes. Ligands that bind through one donor site are monodentate, ligands with two donor sites are bidentate, and those with more than two donor sites are polydentate ligands. For example, ethylene diamine is a bidentate ligand that binds through two nitrogen donor atoms, forming a five-membered ring. EDTA is a polydentate ligand that binds through four oxygen and two nitrogen...
Valence Bond Theory02:42

Valence Bond Theory

Coordination compounds and complexes exhibit different colors, geometries, and magnetic behavior, depending on the metal atom/ion and ligands from which they are composed. In an attempt to explain the bonding and structure of coordination complexes, Linus Pauling proposed the valence bond theory, or VBT, using the concepts of hybridization and the overlapping of the atomic orbitals. According to VBT, the central metal atom or ion (Lewis acid) hybridizes to provide empty orbitals of suitable...
Colors and Magnetism03:02

Colors and Magnetism

Color in Coordination Complexes
When atoms or molecules absorb light at the proper frequency, their electrons are excited to higher-energy orbitals. For many main group atoms and molecules, the absorbed photons are in the ultraviolet range of the electromagnetic spectrum, which cannot be detected by the human eye. For coordination compounds, the energy difference between the d orbitals often allows photons in the visible range to be absorbed and emitted, which is seen as colors by the human eye.
Complexometric Titration: Ligands00:43

Complexometric Titration: Ligands

Different monodentate and polydentate ligands are used as complexing agents in complexometric titration reactions. The formation of complexes by mono- and bidentate ligands involves two or more intermediate steps, limiting their use as complexing agents. In comparison, polydentate ligands can form complexes with metal ions in a single-step process, facilitating sharper end points. This means polydentate ligands, such as amino carboxylic acid derivatives, are most commonly employed in...

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Related Experiment Video

Updated: Jul 5, 2026

Synthesis of a Water-soluble Metal–Organic Complex Array
06:40

Synthesis of a Water-soluble Metal–Organic Complex Array

Published on: October 8, 2016

Multinuclear metal nucleobase complexes.

A Schreiber1, H Rauter, M Krumm

  • 1Fachbereich Chemie Universität Dortmund Dortmund D -44221 Germany.

Metal-Based Drugs
|January 1, 1994
PubMed
Summary
This summary is machine-generated.

Researchers explored multinuclear metal nucleobase complexes, focusing on heteronuclear platinum complexes and novel cyclic structures. This study details the formation of Pt-M bonds and cyclic platinum-uracil complexes, expanding knowledge of coordination chemistry.

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Structure and Coordination Determination of Peptide-metal Complexes Using 1D and 2D 1H NMR
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Structure and Coordination Determination of Peptide-metal Complexes Using 1D and 2D 1H NMR

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Synthesis of a Water-soluble Metal–Organic Complex Array
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Thermochemical Studies of Ni(II) and Zn(II) Ternary Complexes Using Ion Mobility-Mass Spectrometry
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Structure and Coordination Determination of Peptide-metal Complexes Using 1D and 2D 1H NMR
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Structure and Coordination Determination of Peptide-metal Complexes Using 1D and 2D 1H NMR

Published on: December 16, 2013

Area of Science:

  • Coordination Chemistry
  • Supramolecular Chemistry
  • Bioinorganic Chemistry

Background:

  • Metal nucleobase complexes exhibit a remarkable tendency to form multinuclear species.
  • Previous work established well-known polymeric metal nucleobase complexes.
  • Recent research has focused on novel heteronuclear and cyclic structures.

Purpose of the Study:

  • To investigate the formation of heteronuclear metal complexes involving platinum and 1-methylcytosine.
  • To explore the synthesis and properties of cyclic nucleobase complexes derived from cis- and trans-platinum(II) precursors.
  • To establish analogies between cyclic platinum-uracil complexes and organic calixarenes.

Main Methods:

  • Synthesis of heteronuclear platinum-metal complexes via deprotonation of 1-methylcytosine ligands.
  • Preparation of cyclic nucleobase complexes using cis-diammineplatinum(II) precursors.
  • Outlining synthetic strategies for macrocyclic complexes with trans-diammineplatinum(II) linkages.

Main Results:

  • Formation of heteronuclear complexes of type trans-[(amine)(2)Pt(1-MeC-)(2)MY](n+) with Pt-M bond formation.
  • Characterization of a cyclic uracil complex {[(en)Pt(UH-N(1),N(3))](4)}(4+) analogous to calixarenes.
  • Presentation of potential pathways and intermediates for macrocyclic complex synthesis.

Conclusions:

  • Multinuclear metal nucleobase complexes represent a significant area of chemical research.
  • Novel heteronuclear and cyclic platinum complexes with nucleobases have been synthesized and characterized.
  • The study provides insights into the construction of complex metallosupramolecular architectures.