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Updated: Jul 5, 2026

A Manual Small Molecule Screen Approaching High-throughput Using Zebrafish Embryos
07:45

A Manual Small Molecule Screen Approaching High-throughput Using Zebrafish Embryos

Published on: November 8, 2014

Zebrafish: at the nexus of functional and chemical genomics

Andrew Dodd1, David R Greenwood, Andrew L Miller

  • 1School of Biological Sciences, University of Auckland, Private Bag 92019, Auckland 1001, New Zealand.

Biotechnology & Genetic Engineering Reviews
|May 15, 2008
PubMed
Abstract

No abstract available in PubMed .

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Genetic screens are tools used to identify genes and mutations responsible for phenotypes of interest. Genetic screens help identify individuals or a group of people at risk of developing  genetic diseases and help them with early intervention, targeted therapy, and reproductive options.
Forward genetic screens
Forward or “classical” genetic screens involve creating random mutations in an organism’s DNA using radiation, mutagens, or insertion of additional bases, which result in visible changes...