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Related Experiment Video

Updated: Jul 5, 2026

Transcatheter Pulmonary Valve Replacement from Autologous Pericardium with a Self-Expandable Nitinol Stent in an Adult Sheep Model

Transcatheter Pulmonary Valve Replacement from Autologous Pericardium with a Self-Expandable Nitinol Stent in an Adult Sheep Model

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[Stents valves for percutaneous valve replacement].

L K von Segesser¹, K S Kang, S Di Bernardo

¹Service de chirurgie cardiovasculaire, CardioMet, CHUV, 1011 Lausanne.

Revue Medicale Suisse

|May 15, 2008

Summary

Stent-mounted biological valves, compressed for catheter delivery, offer new minimally invasive options for heart valve replacement. Clinical experience is growing, with current efforts focusing on aortic valve implantation.

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Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots

Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots

Published on: May 21, 2017

Area of Science:

Cardiovascular Surgery
Biomedical Engineering
Interventional Cardiology

Context:

Biological valves (porcine and pericardial) have historically been mounted on stents in traditional valve surgery.
Recent advancements allow stent-mounted biological devices to be compressed for transcatheter delivery.
Minimally invasive techniques are transforming cardiac valve replacement procedures.

Purpose:

To review the development and application of stent-mounted biological devices for heart valve implantation.
To explore various implantation routes, including open, trans-vascular, and direct access methods.
To highlight the potential of these devices for video-endoscopic valve replacement.

Summary:

Stent-mounted biological valves can be compressed for delivery via catheter through various access routes (trans-vascular, trans-apical, trans-atrial).
Experimental and clinical implantation has been performed in multiple heart valve positions, including tricuspid, caval, pulmonary, mitral, and aortic.
Significant clinical experience exists for pulmonary valve replacement, with ongoing research targeting aortic valve applications.

Impact:

Enables less invasive heart valve replacement procedures, potentially reducing patient recovery time and complications.
Expands treatment options for patients with valvular heart disease, particularly in the aortic position.
Drives innovation in transcatheter valve technologies and surgical techniques.